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Page 1
Intersection of immune and oncometabolic pathways drives cancer hyperprogression during immunotherapy.
Li G, Choi JE, Kryczek I, Sun Y, Liao P, Li S, Wei S, Grove S, Vatan L, Nelson R, Schaefer G, Allen SG, Sankar K, Fecher LA, Mendiratta-Lala M, Frankel TL, Qin A, Waninger JJ, Tezel A, Alva A, Lao CD, Ramnath N, Cieslik M, Harms PW, Green MD, Chinnaiyan AM, Zou W. Li G, et al. Cancer Cell. 2023 Feb 13;41(2):304-322.e7. doi: 10.1016/j.ccell.2022.12.008. Epub 2023 Jan 12. Cancer Cell. 2023. PMID: 36638784 Free PMC article.
Large-scale phenotyping of patients with long COVID post-hospitalization reveals mechanistic subtypes of disease.
Liew F, Efstathiou C, Fontanella S, Richardson M, Saunders R, Swieboda D, Sidhu JK, Ascough S, Moore SC, Mohamed N, Nunag J, King C, Leavy OC, Elneima O, McAuley HJC, Shikotra A, Singapuri A, Sereno M, Harris VC, Houchen-Wolloff L, Greening NJ, Lone NI, Thorpe M, Thompson AAR, Rowland-Jones SL, Docherty AB, Chalmers JD, Ho LP, Horsley A, Raman B, Poinasamy K, Marks M, Kon OM, Howard LS, Wootton DG, Quint JK, de Silva TI, Ho A, Chiu C, Harrison EM, Greenhalf W, Baillie JK, Semple MG, Turtle L, Evans RA, Wain LV, Brightling C, Thwaites RS, Openshaw PJM; PHOSP-COVID collaborative group; ISARIC investigators. Liew F, et al. Nat Immunol. 2024 Apr;25(4):607-621. doi: 10.1038/s41590-024-01778-0. Epub 2024 Apr 8. Nat Immunol. 2024. PMID: 38589621 Free PMC article.
Abnormal Ventilation-Perfusion Scan Is Associated with Pulmonary Hypertension in Sickle Cell Adults.
Mehari A, Igbineweka N, Allen D, Nichols J, Thein SL, Weir NA. Mehari A, et al. J Nucl Med. 2019 Jan;60(1):86-92. doi: 10.2967/jnumed.118.211466. Epub 2018 Jun 7. J Nucl Med. 2019. PMID: 29880507 Free PMC article.
Data on V/Q scanning are limited in SCD. Our objective was to compare the performance of V/Q scanning with that of CT pulmonary angiography (CTPA) and to report clinical outcomes associated with abnormal V/Q findings. ...Thirty-three patients had a complete d …
Data on V/Q scanning are limited in SCD. Our objective was to compare the performance of V/Q scanning with that of CT pulmonar …
Safety of hospital discharge before return of bowel function after elective colorectal surgery.
EuroSurg Collaborative. EuroSurg Collaborative. Br J Surg. 2020 Apr;107(5):552-559. doi: 10.1002/bjs.11422. Epub 2020 Jan 24. Br J Surg. 2020. PMID: 31976560

The median duration of hospital stay for patients discharged before and after return of bowel function was 5 (i.q.r. 4-7) and 7 (6-8) days respectively (P < 0.001). There were no significant differences in rates of readmission between these groups (6.6 versus 8.0 per ce

…
The median duration of hospital stay for patients discharged before and after return of bowel function was 5 (i.q.r. 4-7) and 7 (6-8) …
Safety and efficacy of non-steroidal anti-inflammatory drugs to reduce ileus after colorectal surgery.
EuroSurg Collaborative. EuroSurg Collaborative. Br J Surg. 2020 Jan;107(2):e161-e169. doi: 10.1002/bjs.11326. Epub 2019 Oct 9. Br J Surg. 2020. PMID: 31595986 Free article.
RESULTS: A total of 4164 patients were included, with a median age of 68 (i.q.r. 57-75) years (54.9 per cent men). Some 1153 (27.7 per cent) received NSAIDs on postoperative days 1-3, of whom 1061 (92.0 per cent) received non-selective cyclo-oxygenase inhibitors. ...
RESULTS: A total of 4164 patients were included, with a median age of 68 (i.q.r. 57-75) years (54.9 per cent men). Some 1153 (27.7 pe …
Selective Inhibition of Coxiella burnetii Replication by the Steroid Hormone Progesterone.
Howard ZP, Omsland A. Howard ZP, et al. Infect Immun. 2020 Nov 16;88(12):e00894-19. doi: 10.1128/IAI.00894-19. Print 2020 Nov 16. Infect Immun. 2020. PMID: 32928965 Free PMC article.
Coxiella burnetii is a zoonotic bacterial obligate intracellular parasite and the cause of query (Q) fever. During natural infection of female animals, C. burnetii shows tropism for the placenta and is associated with late-term abortion, at which time the pathogen titer in …
Coxiella burnetii is a zoonotic bacterial obligate intracellular parasite and the cause of query (Q) fever. During natural infection …
Dendritic calcium signals in rhesus macaque motor cortex drive an optical brain-computer interface.
Trautmann EM, O'Shea DJ, Sun X, Marshel JH, Crow A, Hsueh B, Vesuna S, Cofer L, Bohner G, Allen W, Kauvar I, Quirin S, MacDougall M, Chen Y, Whitmire MP, Ramakrishnan C, Sahani M, Seidemann E, Ryu SI, Deisseroth K, Shenoy KV. Trautmann EM, et al. Nat Commun. 2021 Jun 17;12(1):3689. doi: 10.1038/s41467-021-23884-5. Nat Commun. 2021. PMID: 34140486 Free PMC article.
Natural genetic variation in Drosophila melanogaster reveals genes associated with Coxiella burnetii infection.
Guzman RM, Howard ZP, Liu Z, Oliveira RD, Massa AT, Omsland A, White SN, Goodman AG. Guzman RM, et al. Genetics. 2021 Mar 31;217(3):iyab005. doi: 10.1093/genetics/iyab005. Genetics. 2021. PMID: 33789347 Free PMC article.
The gram-negative bacterium Coxiella burnetii is the causative agent of Query (Q) fever in humans and coxiellosis in livestock. Host genetics are associated with C. burnetii pathogenesis both in humans and animals; however, it remains unknown if specific genes are associat …
The gram-negative bacterium Coxiella burnetii is the causative agent of Query (Q) fever in humans and coxiellosis in livestock. Host …
Characterization of differentiated quiescent and nonquiescent cells in yeast stationary-phase cultures.
Aragon AD, Rodriguez AL, Meirelles O, Roy S, Davidson GS, Tapia PH, Allen C, Joe R, Benn D, Werner-Washburne M. Aragon AD, et al. Mol Biol Cell. 2008 Mar;19(3):1271-80. doi: 10.1091/mbc.e07-07-0666. Epub 2008 Jan 16. Mol Biol Cell. 2008. PMID: 18199684 Free PMC article.
Microarray analysis revealed >1300 mRNAs distinguished Q from NQ fractions. Q cell-specific mRNAs encode proteins involved in membrane maintenance, oxidative stress response, and signal transduction. ...Our results indicate that Q and NQ cells differentiat …
Microarray analysis revealed >1300 mRNAs distinguished Q from NQ fractions. Q cell-specific mRNAs encode proteins involved …
14 results