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Page 1
Did you mean hu zhao tun (2 results)?
Effect of Oral Methylprednisolone on Decline in Kidney Function or Kidney Failure in Patients With IgA Nephropathy: The TESTING Randomized Clinical Trial.
Lv J, Wong MG, Hladunewich MA, Jha V, Hooi LS, Monaghan H, Zhao M, Barbour S, Jardine MJ, Reich HN, Cattran D, Glassock R, Levin A, Wheeler DC, Woodward M, Billot L, Stepien S, Rogers K, Chan TM, Liu ZH, Johnson DW, Cass A, Feehally J, Floege J, Remuzzi G, Wu Y, Agarwal R, Zhang H, Perkovic V; TESTING Study Group. Lv J, et al. JAMA. 2022 May 17;327(19):1888-1898. doi: 10.1001/jama.2022.5368. JAMA. 2022. PMID: 35579642 Free PMC article. Clinical Trial.
Five-day water-only fasting decreased metabolic-syndrome risk factors and increased anti-aging biomarkers without toxicity in a clinical trial of normal-weight individuals.
Jiang Y, Yang X, Dong C, Lu Y, Yin H, Xiao B, Yang X, Chen W, Cheng W, Tian H, Guo L, Hu X, Fang H, Chen W, Li Z, Zhou W, Sun W, Guo X, Li S, Lin Y, He R, Chen X, Liu D, Zhang M, Zhang Y, Zhao H, Zheng P, Seyfried TN, Hoffman RM, Jia W, Ji G, Jia L. Jiang Y, et al. Among authors: zhao h. Clin Transl Med. 2021 Aug;11(8):e502. doi: 10.1002/ctm2.502. Clin Transl Med. 2021. PMID: 34459130 Free PMC article. No abstract available.
A novel oxidative stress- and ferroptosis-related gene prognostic signature for distinguishing cold and hot tumors in colorectal cancer.
Wang X, Xu Y, Dai L, Yu Z, Wang M, Chan S, Sun R, Han Q, Chen J, Zuo X, Wang Z, Hu X, Yang Y, Zhao H, Hu K, Zhang H, Chen W. Wang X, et al. Among authors: zhao h. Front Immunol. 2022 Oct 31;13:1043738. doi: 10.3389/fimmu.2022.1043738. eCollection 2022. Front Immunol. 2022. PMID: 36389694 Free PMC article.
We aimed to develop an oxidative stress- and ferroptosis-related gene (OFRG) prognostic signature to predict the prognosis and therapeutic response in patients with colorectal cancer (CRC). Thirty-four insertion genes between oxidative stress-related genes and ferroptosis- …
We aimed to develop an oxidative stress- and ferroptosis-related gene (OFRG) prognostic signature to predict the prognosis and therapeuti …
Effect of Oral Methylprednisolone on Clinical Outcomes in Patients With IgA Nephropathy: The TESTING Randomized Clinical Trial.
Lv J, Zhang H, Wong MG, Jardine MJ, Hladunewich M, Jha V, Monaghan H, Zhao M, Barbour S, Reich H, Cattran D, Glassock R, Levin A, Wheeler D, Woodward M, Billot L, Chan TM, Liu ZH, Johnson DW, Cass A, Feehally J, Floege J, Remuzzi G, Wu Y, Agarwal R, Wang HY, Perkovic V; TESTING Study Group. Lv J, et al. JAMA. 2017 Aug 1;318(5):432-442. doi: 10.1001/jama.2017.9362. JAMA. 2017. PMID: 28763548 Free PMC article. Clinical Trial.
OBJECTIVE: To evaluate the efficacy and safety of corticosteroids in patients with IgA nephropathy at risk of progression. DESIGN, SETTING, AND PARTICIPANTS: The Therapeutic Evaluation of Steroids in IgA Nephropathy Global (TESTING) study was a multicenter, double-blind, r …
OBJECTIVE: To evaluate the efficacy and safety of corticosteroids in patients with IgA nephropathy at risk of progression. DESIGN, SETTING, …
Device-Based Sympathetic Nerve Regulation for Cardiovascular Diseases.
Li L, Hu Z, Xiong Y, Yao Y. Li L, et al. Among authors: hu z. Front Cardiovasc Med. 2021 Dec 9;8:803984. doi: 10.3389/fcvm.2021.803984. eCollection 2021. Front Cardiovasc Med. 2021. PMID: 34957267 Free PMC article. Review.
Device-based sympathetic nerve (SN) regulation offers a new therapeutic option for some CVDs. Renal denervation (RDN) is the most well-documented method of device-based SN regulation in clinical studies, and several large-scale randomized controlled trials have confirmed i …
Device-based sympathetic nerve (SN) regulation offers a new therapeutic option for some CVDs. Renal denervation (RDN) is the most wel …
The lipid metabolism remodeling: A hurdle in breast cancer therapy.
Xiao Q, Xia M, Tang W, Zhao H, Chen Y, Zhong J. Xiao Q, et al. Among authors: zhao h. Cancer Lett. 2024 Feb 1;582:216512. doi: 10.1016/j.canlet.2023.216512. Epub 2023 Nov 28. Cancer Lett. 2024. PMID: 38036043 Review.
Tumor cells actively or passively remodel lipid metabolism, using the function of lipids in various important cellular life activities to evade therapeutic attack. Breast cancer has become the leading cause of cancer-related deaths in women, which is partly due to thera …
Tumor cells actively or passively remodel lipid metabolism, using the function of lipids in various important cellular life activities to ev …
CTSG Suppresses Colorectal Cancer Progression through Negative Regulation of Akt/mTOR/Bcl2 Signaling Pathway.
Chan S, Wang X, Wang Z, Du Y, Zuo X, Chen J, Sun R, Zhang Q, Lin L, Yang Y, Yu Z, Zhao H, Zhang H, Chen W. Chan S, et al. Among authors: zhao h. Int J Biol Sci. 2023 Apr 17;19(7):2220-2233. doi: 10.7150/ijbs.82000. eCollection 2023. Int J Biol Sci. 2023. PMID: 37151875 Free PMC article.
Altogether, these outcomes demonstrate that CTSG may act as a tumor suppressor gene via Akt/mTOR/Bcl2-mediated anti-apoptotic signaling inactivation, and CTSG represents a potential therapeutic target in CRC....
Altogether, these outcomes demonstrate that CTSG may act as a tumor suppressor gene via Akt/mTOR/Bcl2-mediated anti-apoptotic signaling inac …
Targeting of Discoidin Domain Receptor 2 (DDR2) Prevents Myofibroblast Activation and Neovessel Formation During Pulmonary Fibrosis.
Zhao H, Bian H, Bu X, Zhang S, Zhang P, Yu J, Lai X, Li D, Zhu C, Yao L, Su J. Zhao H, et al. Mol Ther. 2016 Oct;24(10):1734-1744. doi: 10.1038/mt.2016.109. Epub 2016 May 27. Mol Ther. 2016. PMID: 27350126 Free PMC article.
In addition, we confirmed that late treatment of the injured mice with specific siRNA against DDR2 or its kinase inhibitor exhibited therapeutic efficacy against lung fibrosis. Thus, this study not only elucidated novel mechanisms by which DDR2 controls the development of …
In addition, we confirmed that late treatment of the injured mice with specific siRNA against DDR2 or its kinase inhibitor exhibited ther …
Neuregulin Signaling in the Tumor Microenvironment.
Jia R, Zhao H, Wang S. Jia R, et al. Among authors: zhao h. Adv Exp Med Biol. 2021;1270:1-29. doi: 10.1007/978-3-030-47189-7_1. Adv Exp Med Biol. 2021. PMID: 33123990
In this chapter, we focus on the role of neuregulin signaling in the hallmarks of cancer, including cancer initiation and development, metastasis, as well as therapeutic resistance. Moreover, role of neuregulin signaling in the regulation of tumor microenvironment and targ …
In this chapter, we focus on the role of neuregulin signaling in the hallmarks of cancer, including cancer initiation and development, metas …
cDCBLD2 mediates sorafenib resistance in hepatocellular carcinoma by sponging miR-345-5p binding to the TOP2A coding sequence.
Ruan Y, Chen T, Zheng L, Cai J, Zhao H, Wang Y, Tao L, Xu J, Ji L, Cai X. Ruan Y, et al. Among authors: zhao h. Int J Biol Sci. 2023 Aug 28;19(14):4608-4626. doi: 10.7150/ijbs.86227. eCollection 2023. Int J Biol Sci. 2023. PMID: 37781045 Free PMC article.
Sorafenib is a first-line chemotherapy drug for treating advanced hepatocellular carcinoma (HCC). However, its therapeutic effect has been seriously affected by the emergence of sorafenib resistance in HCC patients. ...
Sorafenib is a first-line chemotherapy drug for treating advanced hepatocellular carcinoma (HCC). However, its therapeutic effect has …
120 results