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Re-discovery of MS-347a as a fungicide candidate through a new drug discovery platform with a multidrug-sensitive Saccharomyces cerevisiae screening system and the introduction of a global secondary metabolism regulator, laeA gene.
Honma S, Kimishima A, Kimishima A, Honsho M, Kojima H, Tokiwa T, Nishitomi A, Kato S, Kondo N, Araki Y, Takahashi T, Chinen T, Usui T, Fuji SI, Ito K, Asami Y. Honma S, et al. Among authors: tokiwa t. Biosci Biotechnol Biochem. 2024 Apr 25:zbae050. doi: 10.1093/bbb/zbae050. Online ahead of print. Biosci Biotechnol Biochem. 2024. PMID: 38664007
A Combination Strategy of Multidrug-Sensitive Budding Yeast and Chemical Modifications Enabling to Find a New Overlooked Antifungal Compound, Sakurafusariene, from In-House Fractionated Library.
Kimishima A, Ono Y, Sakai K, Sakai K, Honsho M, Naher K, Tokiwa T, Kojima H, Higo M, Nonaka K, Iwatsuki M, Fuji SI, Chinen T, Usui T, Asami Y. Kimishima A, et al. Among authors: tokiwa t. J Agric Food Chem. 2023 Feb 14. doi: 10.1021/acs.jafc.2c09015. Online ahead of print. J Agric Food Chem. 2023. PMID: 36786603
Total Synthesis of Fusaramin, Enabling Stereochemical Elucidation, Structure-Activity Relationship, and Uncovering the Hidden Antimicrobial Activity against Plant Pathogenic Fungi.
Kimishima A, Hagimoto D, Honsho M, Sakai K, Honma S, Fuji SI, Iwatsuki M, Tokiwa T, Nonaka K, Chinen T, Usui T, Asami Y. Kimishima A, et al. Among authors: tokiwa t. Org Lett. 2024 Jan 26;26(3):597-601. doi: 10.1021/acs.orglett.3c03792. Epub 2024 Jan 10. Org Lett. 2024. PMID: 38198624
A novel aromatic compound from the fungus Synnemellisia sp. FKR-0921.
Tahara A, Tani K, Wakatsuki M, Tokiwa T, Higo M, Nonaka K, Hirose T, Hokari R, Ishiyama A, Iwatsuki M, Watanabe Y, Honsho M, Asami Y, Matsui H, Sunazuka T, Hanaki H, Teruya T, Ishii T. Tahara A, et al. Among authors: tokiwa t. J Antibiot (Tokyo). 2023 Dec;76(12):706-710. doi: 10.1038/s41429-023-00657-4. Epub 2023 Sep 27. J Antibiot (Tokyo). 2023. PMID: 37758818
Antifungal profile against Candida auris clinical isolates of tyroscherin and its new analog produced by the deep-sea-derived fungal strain Scedosporium apiospermum FKJ-0499.
Azami H, Watanabe Y, Sakai K, Nakahara H, Kojima H, Tokiwa T, Nonaka K, Noguchi Y, Nagano Y, Hirose T, Sunazuka T, Matsui H, Arima N, Abe K, Hanaki H, Iwatsuki M. Azami H, et al. Among authors: tokiwa t. J Antibiot (Tokyo). 2024 Mar;77(3):156-162. doi: 10.1038/s41429-023-00696-x. Epub 2024 Jan 11. J Antibiot (Tokyo). 2024. PMID: 38200163
Virgaricins C and D, new pramanicin analogs produced by Apiospora sp. FKI-8058.
Kimura SI, Watanabe Y, Mikasa Y, Miyano R, Tokiwa T, Nonaka K, Nakashima T, Noguchi Y, Hirose T, Sunazuka T, Hokari R, Ishiyama A, Iwatsuki M. Kimura SI, et al. Among authors: tokiwa t. J Antibiot (Tokyo). 2024 Apr;77(4):206-213. doi: 10.1038/s41429-023-00699-8. Epub 2024 Feb 2. J Antibiot (Tokyo). 2024. PMID: 38302743
Exploring natural microbial resources for the discovery of anti-malarial compounds.
Waluyo D, Prabandari EE, Pramisandi A, Hidayati DN, Chrisnayanti E, Puspitasari DJ, Dewi D, Suryani, Kristiningrum, Oktaviani AN, Afrianti KR, Nonaka K, Matsumoto A, Tokiwa T, Adipratiwi N, Ariyani T, Hartuti ED, Putri TZ, Rahmawati Y, Inaoka DK, Miyazaki Y, Sakura T, Nurlaila, Siska E, Kurnia K, Bernawati P, Melinda, Mahsunah AH, Nugroho NB, Mori M, Dobashi K, Yamashita M, Nurkanto A, Watanabe A, Shiomi K, Wibowo AE, Nozaki T. Waluyo D, et al. Among authors: tokiwa t. Parasitol Int. 2021 Dec;85:102432. doi: 10.1016/j.parint.2021.102432. Epub 2021 Aug 5. Parasitol Int. 2021. PMID: 34363974 Free article.
172 results