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Single-chain antibody conjugated to a cage amine chelator and labeled with positron-emitting copper-64 for diagnostic imaging of activated platelets.
Alt K, Paterson BM, Ardipradja K, Schieber C, Buncic G, Lim B, Poniger SS, Jakoby B, Wang X, O'Keefe GJ, Tochon-Danguy HJ, Scott AM, Ackermann U, Peter K, Donnelly PS, Hagemeyer CE. Alt K, et al. Among authors: donnelly ps. Mol Pharm. 2014 Aug 4;11(8):2855-63. doi: 10.1021/mp500209a. Epub 2014 Jul 14. Mol Pharm. 2014. PMID: 24999533
Engineering poly(ethylene glycol) particles for improved biodistribution.
Cui J, De Rose R, Alt K, Alcantara S, Paterson BM, Liang K, Hu M, Richardson JJ, Yan Y, Jeffery CM, Price RI, Peter K, Hagemeyer CE, Donnelly PS, Kent SJ, Caruso F. Cui J, et al. Among authors: donnelly ps. ACS Nano. 2015 Feb 24;9(2):1571-80. doi: 10.1021/nn5061578. Epub 2015 Jan 21. ACS Nano. 2015. PMID: 25712853
A versatile approach for the site-specific modification of recombinant antibodies using a combination of enzyme-mediated bioconjugation and click chemistry.
Alt K, Paterson BM, Westein E, Rudd SE, Poniger SS, Jagdale S, Ardipradja K, Connell TU, Krippner GY, Nair AK, Wang X, Tochon-Danguy HJ, Donnelly PS, Peter K, Hagemeyer CE. Alt K, et al. Among authors: donnelly ps. Angew Chem Int Ed Engl. 2015 Jun 22;54(26):7515-9. doi: 10.1002/anie.201411507. Epub 2015 May 11. Angew Chem Int Ed Engl. 2015. PMID: 25962581
167 results