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S670, an amide derivative of 3-O-acetyl-11-keto-β-boswellic acid, induces ferroptosis in human glioblastoma cells by generating ROS and inhibiting STX17-mediated fusion of autophagosome and lysosome.
Yang YH, Li W, Ren LW, Yang H, Zhang YZ, Zhang S, Hao Y, Yu DK, Tong RS, Du GH, Shi JY, Wang JH. Yang YH, et al. Among authors: yang h. Acta Pharmacol Sin. 2024 Jan;45(1):209-222. doi: 10.1038/s41401-023-01157-9. Epub 2023 Sep 25. Acta Pharmacol Sin. 2024. PMID: 37749236
Progress of studies on natural products for glioblastoma therapy.
Xu F, Yang YH, Yang H, Li W, Hao Y, Zhang S, Zhang YZ, Cao WX, Li XX, Du GH, Ji TF, Wang JH. Xu F, et al. Among authors: yang yh, yang h. J Asian Nat Prod Res. 2024 Jan;26(1):154-176. doi: 10.1080/10286020.2023.2300367. Epub 2024 Feb 6. J Asian Nat Prod Res. 2024. PMID: 38321773 Review.
Discovery of a PROTAC degrader for METTL3-METTL14 complex.
Du W, Huang Y, Chen X, Deng Y, Sun Y, Yang H, Shi Q, Wu F, Liu G, Huang H, Ding J, Huang X, Xu S. Du W, et al. Among authors: yang h. Cell Chem Biol. 2024 Jan 18;31(1):177-183.e17. doi: 10.1016/j.chembiol.2023.12.009. Epub 2024 Jan 8. Cell Chem Biol. 2024. PMID: 38194973
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