Progress of studies on natural products for glioblastoma therapy

J Asian Nat Prod Res. 2024 Jan;26(1):154-176. doi: 10.1080/10286020.2023.2300367. Epub 2024 Feb 6.

Abstract

Glioblastoma (GBM) is the most common, malignant, and lethal primary brain tumor in adults. Up to now, the chemotherapy approaches for GBM are limited. Therefore, more studies on identifying and exploring new chemotherapy drugs or strategies overcome the GBM are essential. Natural products are an important source of drugs against various human diseases including cancers. With the better understanding of the molecular etiology of GBM, the development of new anti-GBM drugs has been increasing. Here, we summarized recent researches of natural products for the GBM therapy and their potential mechanisms in details, which will provide new ideas for the research on natural products and promote developing drugs from nature products for GBM therapy.

Keywords: Glioblastoma/glioma; anticancer; medications; natural products.

Publication types

  • Review

MeSH terms

  • Biological Products* / pharmacology
  • Biological Products* / therapeutic use
  • Brain Neoplasms* / drug therapy
  • Brain Neoplasms* / pathology
  • Glioblastoma* / drug therapy
  • Glioblastoma* / pathology
  • Humans

Substances

  • Biological Products