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The JAK3Q988P mutation reveals oncogenic potential and resistance to ruxolitinib.
Lahera A, Vela-Martín L, Fernández-Navarro P, Llamas P, López-Lorenzo JL, Cornago J, Santos J, Fernández-Piqueras J, Villa-Morales M. Lahera A, et al. Among authors: villa morales m. Mol Carcinog. 2024 Jan;63(1):5-10. doi: 10.1002/mc.23632. Epub 2023 Sep 15. Mol Carcinog. 2024. PMID: 37712558
Exploiting the passenger ACO1-deficiency arising from 9p21 deletions to kill T-cell lymphoblastic neoplasia cells.
Gonzalez-Sanchez L, Cobos-Fernandez MA, Lopez-Nieva P, Villa-Morales M, Stamatakis K, Cuezva JM, Marin-Rubio JL, Vazquez-Dominguez I, Gonzalez-Vasconcellos I, Salido E, Llamas P, Lopez-Lorenzo JL, Santos J, Fernandez-Piqueras J. Gonzalez-Sanchez L, et al. Among authors: villa morales m. Carcinogenesis. 2020 Aug 12;41(8):1113-1122. doi: 10.1093/carcin/bgz185. Carcinogenesis. 2020. PMID: 31734690 Free article.
EPHA7, a new target gene for 6q deletion in T-cell lymphoblastic lymphomas.
López-Nieva P, Vaquero C, Fernández-Navarro P, González-Sánchez L, Villa-Morales M, Santos J, Esteller M, Fernández-Piqueras J. López-Nieva P, et al. Carcinogenesis. 2012 Feb;33(2):452-8. doi: 10.1093/carcin/bgr271. Epub 2011 Nov 22. Carcinogenesis. 2012. PMID: 22114070
A Dual Role for FADD in Human Precursor T-Cell Neoplasms.
Marín-Rubio JL, Vela-Martín L, Gudgeon J, Pérez-Gómez E, Sidgwick FR, Trost M, Cunningham DL, Santos J, Fernández-Piqueras J, Villa-Morales M. Marín-Rubio JL, et al. Among authors: villa morales m. Int J Mol Sci. 2022 Dec 2;23(23):15157. doi: 10.3390/ijms232315157. Int J Mol Sci. 2022. PMID: 36499482 Free PMC article.
SOCS3 deregulation contributes to aberrant activation of the JAK/STAT pathway in precursor T-cell neoplasms.
Lahera A, López-Nieva P, Alarcón H, Marín-Rubio JL, Cobos-Fernández MÁ, Fernández-Navarro P, Fernández AF, Vela-Martín L, Sastre I, Ruiz-García S, Llamas P, López-Lorenzo JL, Cornago J, Santos J, Fernández-Piqueras J, Villa-Morales M. Lahera A, et al. Among authors: villa morales m. Br J Haematol. 2023 May;201(4):718-724. doi: 10.1111/bjh.18694. Epub 2023 Feb 14. Br J Haematol. 2023. PMID: 36786170
Comprehensive characterization of a novel, oncogenic and targetable SEPTIN6::ABL2 fusion in T-ALL.
Lahera A, Vela-Martín L, López-Nieva P, Salgado RN, Rodríguez-Perales S, Torres-Ruiz R, López-Lorenzo JL, Cornago J, Llamas P, Fernández-Navarro P, Sánchez-Domínguez R, Segovia JC, Sastre I, Cobos-Fernández MÁ, Menéndez P, Santos J, Fernández-Piqueras J, Villa-Morales M. Lahera A, et al. Among authors: villa morales m. Br J Haematol. 2023 Aug;202(3):693-698. doi: 10.1111/bjh.18901. Epub 2023 Jun 2. Br J Haematol. 2023. PMID: 37264982 No abstract available.
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