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Multistage and transmission-blocking targeted antimalarials discovered from the open-source MMV Pandemic Response Box.
Reader J, van der Watt ME, Taylor D, Le Manach C, Mittal N, Ottilie S, Theron A, Moyo P, Erlank E, Nardini L, Venter N, Lauterbach S, Bezuidenhout B, Horatscheck A, van Heerden A, Spillman NJ, Cowell AN, Connacher J, Opperman D, Orchard LM, Llinás M, Istvan ES, Goldberg DE, Boyle GA, Calvo D, Mancama D, Coetzer TL, Winzeler EA, Duffy J, Koekemoer LL, Basarab G, Chibale K, Birkholtz LM. Reader J, et al. Among authors: moyo p. Nat Commun. 2021 Jan 11;12(1):269. doi: 10.1038/s41467-020-20629-8. Nat Commun. 2021. PMID: 33431834 Free PMC article.
Benzimidazole Derivatives Are Potent against Multiple Life Cycle Stages of Plasmodium falciparum Malaria Parasites.
Leshabane M, Dziwornu GA, Coertzen D, Reader J, Moyo P, van der Watt M, Chisanga K, Nsanzubuhoro C, Ferger R, Erlank E, Venter N, Koekemoer L, Chibale K, Birkholtz LM. Leshabane M, et al. Among authors: moyo p. ACS Infect Dis. 2021 Jul 9;7(7):1945-1955. doi: 10.1021/acsinfecdis.0c00910. Epub 2021 Mar 5. ACS Infect Dis. 2021. PMID: 33673735 Free article.
Use of hyphenated analytical techniques to identify the bioactive constituents of Gunnera perpensa L., a South African medicinal plant, which potently inhibit SARS-CoV-2 spike glycoprotein-host ACE2 binding.
Invernizzi L, Moyo P, Cassel J, Isaacs FJ, Salvino JM, Montaner LJ, Tietjen I, Maharaj V. Invernizzi L, et al. Among authors: moyo p. Anal Bioanal Chem. 2022 May;414(13):3971-3985. doi: 10.1007/s00216-022-04041-3. Epub 2022 Apr 14. Anal Bioanal Chem. 2022. PMID: 35419694 Free PMC article.
115 results