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Synthesis, binding assays, cytotoxic activity and docking studies of benzimidazole and benzothiophene derivatives with selective affinity for the CB2 cannabinoid receptor.
Romero-Parra J, Mella-Raipán J, Palmieri V, Allarà M, Torres MJ, Pessoa-Mahana H, Iturriaga-Vásquez P, Escobar R, Faúndez M, Di Marzo V, Pessoa-Mahana CD. Romero-Parra J, et al. Eur J Med Chem. 2016 Nov 29;124:17-35. doi: 10.1016/j.ejmech.2016.08.005. Epub 2016 Aug 5. Eur J Med Chem. 2016. PMID: 27560280
New Pyridone-Based Derivatives as Cannabinoid Receptor Type 2 Agonists.
Faúndez-Parraguez M, Alarcón-Miranda C, Cho YH, Pessoa-Mahana H, Gallardo-Garrido C, Chung H, Faúndez M, Pessoa-Mahana D. Faúndez-Parraguez M, et al. Among authors: pessoa mahana h. Int J Mol Sci. 2021 Oct 18;22(20):11212. doi: 10.3390/ijms222011212. Int J Mol Sci. 2021. PMID: 34681877 Free PMC article.
Design, synthesis, biological evaluation and binding mode modeling of benzimidazole derivatives targeting the cannabinoid receptor type 1.
Espinosa-Bustos C, Lagos CF, Romero-Parra J, Zárate AM, Mella-Raipán J, Pessoa-Mahana H, Recabarren-Gajardo G, Iturriaga-Vásquez P, Tapia RA, Pessoa-Mahana CD. Espinosa-Bustos C, et al. Arch Pharm (Weinheim). 2015 Feb;348(2):81-8. doi: 10.1002/ardp.201400201. Epub 2015 Jan 13. Arch Pharm (Weinheim). 2015. PMID: 25641513
Synthesis and biological evaluation of potential acetylcholinesterase inhibitors based on a benzoxazine core.
Méndez-Rojas C, Quiroz G, Faúndez M, Gallardo-Garrido C, Pessoa-Mahana CD, Chung H, Gallardo-Toledo E, Saitz-Barría C, Araya-Maturana R, Kogan MJ, Zúñiga-López MC, Iturriaga-Vásquez P, Valenzuela-Gutiérrez C, Pessoa-Mahana H. Méndez-Rojas C, et al. Arch Pharm (Weinheim). 2018 May;351(5):e1800024. doi: 10.1002/ardp.201800024. Epub 2018 Apr 3. Arch Pharm (Weinheim). 2018. PMID: 29611620
Synthesis, in vitro evaluation and molecular docking of a new class of indolylpropyl benzamidopiperazines as dual AChE and SERT ligands for Alzheimer's disease.
Rodríguez-Lavado J, Gallardo-Garrido C, Mallea M, Bustos V, Osorio R, Hödar-Salazar M, Chung H, Araya-Maturana R, Lorca M, Pessoa-Mahana CD, Mella-Raipán J, Saitz C, Jaque P, Reyes-Parada M, Iturriaga-Vásquez P, Pessoa-Mahana H. Rodríguez-Lavado J, et al. Among authors: pessoa mahana h. Eur J Med Chem. 2020 Jul 15;198:112368. doi: 10.1016/j.ejmech.2020.112368. Epub 2020 Apr 29. Eur J Med Chem. 2020. PMID: 32388114
31 results