Outeda P - Search Results

1

A novel ARPKD mouse model with near-complete deletion of the Polycystic Kidney and Hepatic Disease 1 (Pkhd1) genomic locus presents with multiple phenotypes but not renal cysts.

Ishimoto Y, Menezes LF, Zhou F, Yoshida T, Komori T, Qiu J, Young MF, Lu H, Potapova S, Outeda P, Watnick T, Germino GG. Ishimoto Y, et al. Among authors: outeda p. Kidney Int. 2023 Sep;104(3):611-616. doi: 10.1016/j.kint.2023.05.027. Epub 2023 Jul 5. Kidney Int. 2023. PMID: 37419448 No abstract available.

2

A novel pattern of mutation in uromodulin disorders: autosomal dominant medullary cystic kidney disease type 2, familial juvenile hyperuricemic nephropathy, and autosomal dominant glomerulocystic kidney disease.

Lens XM, Banet JF, Outeda P, Barrio-Lucía V. Lens XM, et al. Among authors: outeda p. Am J Kidney Dis. 2005 Jul;46(1):52-7. doi: 10.1053/j.ajkd.2005.04.003. Am J Kidney Dis. 2005. PMID: 15983957

3

Genomic organization and mutation screening of the human ortholog of Pkdr1 associated with polycystic kidney disease in the rat.

Kaisaki PJ, Bergmann C, Brown JH, Outeda P, Lens XM, Peters DJ, Gretz N, Gauguier D, Bihoreau MT. Kaisaki PJ, et al. Among authors: outeda p. Eur J Med Genet. 2008 Jul-Aug;51(4):325-31. doi: 10.1016/j.ejmg.2008.02.007. Epub 2008 Mar 16. Eur J Med Genet. 2008. PMID: 18434273

4

Pkd1 and Pkd2 are required for normal placental development.

Garcia-Gonzalez MA, Outeda P, Zhou Q, Zhou F, Menezes LF, Qian F, Huso DL, Germino GG, Piontek KB, Watnick T. Garcia-Gonzalez MA, et al. Among authors: outeda p. PLoS One. 2010 Sep 16;5(9):e12821. doi: 10.1371/journal.pone.0012821. PLoS One. 2010. PMID: 20862291 Free PMC article.

5

Polycystin signaling is required for directed endothelial cell migration and lymphatic development.

Outeda P, Huso DL, Fisher SA, Halushka MK, Kim H, Qian F, Germino GG, Watnick T. Outeda P, et al. Cell Rep. 2014 May 8;7(3):634-44. doi: 10.1016/j.celrep.2014.03.064. Epub 2014 Apr 24. Cell Rep. 2014. PMID: 24767998 Free PMC article.

6

Ciliary membrane proteins traffic through the Golgi via a Rabep1/GGA1/Arl3-dependent mechanism.

Kim H, Xu H, Yao Q, Li W, Huang Q, Outeda P, Cebotaru V, Chiaravalli M, Boletta A, Piontek K, Germino GG, Weinman EJ, Watnick T, Qian F. Kim H, et al. Among authors: outeda p. Nat Commun. 2014 Nov 18;5:5482. doi: 10.1038/ncomms6482. Nat Commun. 2014. PMID: 25405894 Free PMC article.

7

Inhibition of histone deacetylase 6 activity reduces cyst growth in polycystic kidney disease.

Cebotaru L, Liu Q, Yanda MK, Boinot C, Outeda P, Huso DL, Watnick T, Guggino WB, Cebotaru V. Cebotaru L, et al. Among authors: outeda p. Kidney Int. 2016 Jul;90(1):90-9. doi: 10.1016/j.kint.2016.01.026. Epub 2016 Mar 25. Kidney Int. 2016. PMID: 27165822 Free PMC article.

8

The polycystin complex mediates Wnt/Ca(2+) signalling.

Kim S, Nie H, Nesin V, Tran U, Outeda P, Bai CX, Keeling J, Maskey D, Watnick T, Wessely O, Tsiokas L. Kim S, et al. Among authors: outeda p. Nat Cell Biol. 2016 Jul;18(7):752-764. doi: 10.1038/ncb3363. Epub 2016 May 23. Nat Cell Biol. 2016. PMID: 27214281 Free PMC article.

9

A novel model of autosomal recessive polycystic kidney questions the role of the fibrocystin C-terminus in disease mechanism.

Outeda P, Menezes L, Hartung EA, Bridges S, Zhou F, Zhu X, Xu H, Huang Q, Yao Q, Qian F, Germino GG, Watnick T. Outeda P, et al. Kidney Int. 2017 Nov;92(5):1130-1144. doi: 10.1016/j.kint.2017.04.027. Epub 2017 Jul 18. Kidney Int. 2017. PMID: 28729032 Free PMC article.

10

NEDD4-family E3 ligase dysfunction due to PKHD1/Pkhd1 defects suggests a mechanistic model for ARPKD pathobiology.

Kaimori JY, Lin CC, Outeda P, Garcia-Gonzalez MA, Menezes LF, Hartung EA, Li A, Wu G, Fujita H, Sato Y, Nakanuma Y, Yamamoto S, Ichimaru N, Takahara S, Isaka Y, Watnick T, Onuchic LF, Guay-Woodford LM, Germino GG. Kaimori JY, et al. Among authors: outeda p. Sci Rep. 2017 Aug 10;7(1):7733. doi: 10.1038/s41598-017-08284-4. Sci Rep. 2017. PMID: 28798345 Free PMC article.

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