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A novel ARPKD mouse model with near-complete deletion of the Polycystic Kidney and Hepatic Disease 1 (Pkhd1) genomic locus presents with multiple phenotypes but not renal cysts.
Ishimoto Y, Menezes LF, Zhou F, Yoshida T, Komori T, Qiu J, Young MF, Lu H, Potapova S, Outeda P, Watnick T, Germino GG. Ishimoto Y, et al. Among authors: menezes lf. Kidney Int. 2023 Sep;104(3):611-616. doi: 10.1016/j.kint.2023.05.027. Epub 2023 Jul 5. Kidney Int. 2023. PMID: 37419448 No abstract available.
Pkd1 and Pkd2 are required for normal placental development.
Garcia-Gonzalez MA, Outeda P, Zhou Q, Zhou F, Menezes LF, Qian F, Huso DL, Germino GG, Piontek KB, Watnick T. Garcia-Gonzalez MA, et al. Among authors: menezes lf. PLoS One. 2010 Sep 16;5(9):e12821. doi: 10.1371/journal.pone.0012821. PLoS One. 2010. PMID: 20862291 Free PMC article.
Murine Models of Polycystic Kidney Disease.
Menezes LF, Germino GG. Menezes LF, et al. Drug Discov Today Dis Mech. 2013 Dec 1;10(3-4):e153-e158. doi: 10.1016/j.ddmec.2013.10.002. Drug Discov Today Dis Mech. 2013. PMID: 25013443 Free PMC article.
49 results