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In vivo Polycystin-1 interactome using a novel Pkd1 knock-in mouse model.
Lin CC, Menezes LF, Qiu J, Pearson E, Zhou F, Ishimoto Y, Anderson DE, Germino GG. Lin CC, et al. Among authors: germino gg. PLoS One. 2023 Aug 4;18(8):e0289778. doi: 10.1371/journal.pone.0289778. eCollection 2023. PLoS One. 2023. PMID: 37540694 Free PMC article.
A novel ARPKD mouse model with near-complete deletion of the Polycystic Kidney and Hepatic Disease 1 (Pkhd1) genomic locus presents with multiple phenotypes but not renal cysts.
Ishimoto Y, Menezes LF, Zhou F, Yoshida T, Komori T, Qiu J, Young MF, Lu H, Potapova S, Outeda P, Watnick T, Germino GG. Ishimoto Y, et al. Among authors: germino gg. Kidney Int. 2023 Sep;104(3):611-616. doi: 10.1016/j.kint.2023.05.027. Epub 2023 Jul 5. Kidney Int. 2023. PMID: 37419448 No abstract available.
Mechanisms of Cyst Development in Polycystic Kidney Disease.
Qiu J, Germino GG, Menezes LF. Qiu J, et al. Among authors: germino gg. Adv Kidney Dis Health. 2023 May;30(3):209-219. doi: 10.1053/j.akdh.2023.03.001. Adv Kidney Dis Health. 2023. PMID: 37088523 Free PMC article. Review.
Pathway identification through transcriptome analysis.
Terabayashi T, Germino GG, Menezes LF. Terabayashi T, et al. Among authors: germino gg. Cell Signal. 2020 Oct;74:109701. doi: 10.1016/j.cellsig.2020.109701. Epub 2020 Jul 7. Cell Signal. 2020. PMID: 32649993 Free PMC article. Review.
A cleavage product of Polycystin-1 is a mitochondrial matrix protein that affects mitochondria morphology and function when heterologously expressed.
Lin CC, Kurashige M, Liu Y, Terabayashi T, Ishimoto Y, Wang T, Choudhary V, Hobbs R, Liu LK, Lee PH, Outeda P, Zhou F, Restifo NP, Watnick T, Kawano H, Horie S, Prinz W, Xu H, Menezes LF, Germino GG. Lin CC, et al. Among authors: germino gg. Sci Rep. 2018 Feb 9;8(1):2743. doi: 10.1038/s41598-018-20856-6. Sci Rep. 2018. PMID: 29426897 Free PMC article.
A Report of the 24th Annual Congress on Women's Health-Workshop on Transforming Women's Health: From Research to Practice.
Plank-Bazinet JL, Sampson A, Kornstein SG, Germino GG, Robert-Guroff M, Gilman SE, Wetherington CL, Cook N, Cornelison TL, Begg L, Clayton JA. Plank-Bazinet JL, et al. Among authors: germino gg. J Womens Health (Larchmt). 2018 Jan;27(1):115-120. doi: 10.1089/jwh.2017.29016.orwh. J Womens Health (Larchmt). 2018. PMID: 29341869 Free PMC article.
NEDD4-family E3 ligase dysfunction due to PKHD1/Pkhd1 defects suggests a mechanistic model for ARPKD pathobiology.
Kaimori JY, Lin CC, Outeda P, Garcia-Gonzalez MA, Menezes LF, Hartung EA, Li A, Wu G, Fujita H, Sato Y, Nakanuma Y, Yamamoto S, Ichimaru N, Takahara S, Isaka Y, Watnick T, Onuchic LF, Guay-Woodford LM, Germino GG. Kaimori JY, et al. Among authors: germino gg. Sci Rep. 2017 Aug 10;7(1):7733. doi: 10.1038/s41598-017-08284-4. Sci Rep. 2017. PMID: 28798345 Free PMC article.
120 results