Zhang L - Search Results

1

Managing Drug-Drug Interactions in Older Adults.

Zhou Z, Slattum PW, Ke A, Zhang L. Zhou Z, et al. Among authors: zhang l. J Clin Pharmacol. 2023 Oct;63(10):1083-1090. doi: 10.1002/jcph.2299. Epub 2023 Jul 26. J Clin Pharmacol. 2023. PMID: 37408371 No abstract available.

2

New era in drug interaction evaluation: US Food and Drug Administration update on CYP enzymes, transporters, and the guidance process.

Huang SM, Strong JM, Zhang L, Reynolds KS, Nallani S, Temple R, Abraham S, Habet SA, Baweja RK, Burckart GJ, Chung S, Colangelo P, Frucht D, Green MD, Hepp P, Karnaukhova E, Ko HS, Lee JI, Marroum PJ, Norden JM, Qiu W, Rahman A, Sobel S, Stifano T, Thummel K, Wei XX, Yasuda S, Zheng JH, Zhao H, Lesko LJ. Huang SM, et al. Among authors: zhang l. J Clin Pharmacol. 2008 Jun;48(6):662-70. doi: 10.1177/0091270007312153. Epub 2008 Mar 31. J Clin Pharmacol. 2008. PMID: 18378963 Review.

3

Review of P-gp inhibition data in recently approved new drug applications: utility of the proposed [I(1) ]/IC(50) and [I(2) ]/IC(50) criteria in the P-gp decision tree.

Agarwal S, Arya V, Zhang L. Agarwal S, et al. Among authors: zhang l. J Clin Pharmacol. 2013 Feb;53(2):228-33. doi: 10.1177/0091270011436344. J Clin Pharmacol. 2013. PMID: 23436268 No abstract available.

4

Emerging Clinical Importance of Hepatic Organic Cation Transporter 1 (OCT1) in Drug Pharmacokinetics, Dynamics, Pharmacogenetic Variability, and Drug Interactions.

Zamek-Gliszczynski MJ, Giacomini KM, Zhang L. Zamek-Gliszczynski MJ, et al. Among authors: zhang l. Clin Pharmacol Ther. 2018 May;103(5):758-760. doi: 10.1002/cpt.941. Epub 2017 Nov 28. Clin Pharmacol Ther. 2018. PMID: 29193038

5

Influence of Transporter Polymorphisms on Drug Disposition and Response: A Perspective From the International Transporter Consortium.

Yee SW, Brackman DJ, Ennis EA, Sugiyama Y, Kamdem LK, Blanchard R, Galetin A, Zhang L, Giacomini KM. Yee SW, et al. Among authors: zhang l. Clin Pharmacol Ther. 2018 Nov;104(5):803-817. doi: 10.1002/cpt.1098. Epub 2018 May 31. Clin Pharmacol Ther. 2018. PMID: 29679469 Free PMC article. Review.

6

Use of Physiologically Based Pharmacokinetic Modeling to Evaluate the Effect of Chronic Kidney Disease on the Disposition of Hepatic CYP2C8 and OATP1B Drug Substrates.

Tan ML, Zhao P, Zhang L, Ho YF, Varma MVS, Neuhoff S, Nolin TD, Galetin A, Huang SM. Tan ML, et al. Among authors: zhang l. Clin Pharmacol Ther. 2019 Mar;105(3):719-729. doi: 10.1002/cpt.1205. Epub 2018 Oct 26. Clin Pharmacol Ther. 2019. PMID: 30074626 Free PMC article.

7

FDA Public Meeting Report on "Drug Interactions With Hormonal Contraceptives: Public Health and Drug Development Implications".

Akbar M, Berry-Bibee E, Blithe DL, Day RS, Edelman A, Höchel J, Jamshidi R, Kim MJ, Li L, Purohit VS, Turpin JA, Scott PE, Strauss DG, Sun H, Tepper NK, Zhang L, Yu C. Akbar M, et al. Among authors: zhang l. J Clin Pharmacol. 2018 Dec;58(12):1655-1665. doi: 10.1002/jcph.1285. Epub 2018 Aug 24. J Clin Pharmacol. 2018. PMID: 30144093 Free PMC article.

8

Transporters in Drug Development: Scientific and Regulatory Considerations.

Zhang L, Huang SM, Reynolds K, Madabushi R, Zineh I. Zhang L, et al. Clin Pharmacol Ther. 2018 Nov;104(5):793-796. doi: 10.1002/cpt.1214. Epub 2018 Sep 30. Clin Pharmacol Ther. 2018. PMID: 30270426

9

Generating Model Integrated Evidence for Generic Drug Development and Assessment.

Zhao L, Kim MJ, Zhang L, Lionberger R. Zhao L, et al. Among authors: zhang l. Clin Pharmacol Ther. 2019 Feb;105(2):338-349. doi: 10.1002/cpt.1282. Epub 2019 Jan 20. Clin Pharmacol Ther. 2019. PMID: 30414386

10

Comparing Various In Vitro Prediction Methods to Assess the Potential of a Drug to Inhibit P-glycoprotein (P-gp) Transporter In Vivo.

Zhou T, Arya V, Zhang L. Zhou T, et al. Among authors: zhang l. J Clin Pharmacol. 2019 Aug;59(8):1049-1060. doi: 10.1002/jcph.1413. Epub 2019 Mar 29. J Clin Pharmacol. 2019. PMID: 30924955 Review.

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