Managing Drug-Drug Interactions in Older Adults

J Clin Pharmacol. 2023 Oct;63(10):1083-1090. doi: 10.1002/jcph.2299. Epub 2023 Jul 26.

Authors

Zhu Zhou¹, Patricia W Slattum², Alice Ke³, Lei Zhang⁴

Affiliations

¹ Department of Chemistry, York College, City University of New York, Jamaica, NY, USA.
² Virginia Center on Aging, Virginia Commonwealth University, Richmond, VA, USA.
³ Certara UK Limited (Simcyp Division), Sheffield, UK.
⁴ Office of Research and Standards, Office of Generic Drugs, US Food and Drug Administration, Silver Spring, MD, USA.

PMID: 37408371
PMCID: PMC10529698 (available on 2024-10-01)
DOI: 10.1002/jcph.2299

No abstract available

Keywords: drug-drug interactions; older adults; pharmacodynamics; pharmacokinetics; physilogically based pharmacokinetic (PBPK).

Publication types

Research Support, N.I.H., Extramural

MeSH terms

Aged
Computer Simulation
Drug Interactions
Humans
Models, Biological*
Pharmacokinetics*

Grants and funding

R16 GM146679/GM/NIGMS NIH HHS/United States