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1,4-Diurea- and 1,4-Dithiourea-Substituted Aromatic Derivatives Selectively Inhibit α-Synuclein Oligomer Formation In Vitro.
ACS Omega. 2023 Dec 19;9(1):1216-1229. doi: 10.1021/acsomega.3c07453. eCollection 2024 Jan 9.
ACS Omega. 2023.
PMID: 38222653
Free PMC article.
Evaluation of N- and O-Linked Indole Triazines for a Dual Effect on α-Synuclein and Tau Aggregation.
Ramirez E, Ganegamage SK, Min S, Patel H, Ogunware A, Plascencia-Villa G, Alnakhala H, Shimanaka K, Tripathi A, Wang KW, Zhu X, Rochet JC, Kuo MH, Counts SE, Perry G, Dettmer U, Lasagna-Reeves CA, Fortin JS.
Ramirez E, et al. Among authors: ganegamage sk.
ACS Chem Neurosci. 2023 Nov 1;14(21):3913-3927. doi: 10.1021/acschemneuro.3c00464. Epub 2023 Oct 11.
ACS Chem Neurosci. 2023.
PMID: 37818657
Free article.
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Dual and Panchromatic Emission from N-Aryl-phenanthridinones: Extension of the Seesaw Photophysical Model with a Slight Twist.
Ganegamage SK, Zou Y, Heagy MD.
Ganegamage SK, et al.
J Org Chem. 2023 Aug 18;88(16):11424-11433. doi: 10.1021/acs.joc.2c03063. Epub 2023 Jul 3.
J Org Chem. 2023.
PMID: 37399167
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Discovery of 4-aminoindole carboxamide derivatives to curtail alpha-synuclein and tau isoform 2N4R oligomer formation.
Ramirez E, Min S, Ganegamage SK, Shimanaka K, Sosa MG, Dettmer U, Rochet JC, Fortin JS.
Ramirez E, et al. Among authors: ganegamage sk.
Results Chem. 2023 Jan;5:100938. doi: 10.1016/j.rechem.2023.100938. Epub 2023 Apr 28.
Results Chem. 2023.
PMID: 37346091
Free PMC article.
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5-Nitro-1,2-benzothiazol-3-amine and N-Ethyl-1-[(ethylcarbamoyl)(5-nitro-1,2-benzothiazol-3-yl)amino]formamide Modulate α-Synuclein and Tau Aggregation.
Ramirez E, Ganegamage SK, Elbatrawy AA, Alnakhala H, Shimanaka K, Tripathi A, Min S, Rochet JC, Dettmer U, Fortin JS.
Ramirez E, et al. Among authors: ganegamage sk.
ACS Omega. 2023 May 23;8(22):20102-20115. doi: 10.1021/acsomega.3c02668. eCollection 2023 Jun 6.
ACS Omega. 2023.
PMID: 37305264
Free PMC article.
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Anti-fibrillization effects of sulfonamide derivatives on α-synuclein and hyperphosphorylated tau isoform 1N4R.
Fortin JS, Shimanaka K, Saraswati AP, Liu M, Wang KW, Hagar HT, Maity S, Ganegamage SK, Ellsworth E, Counts SE, Borhan B, Dettmer U, Kuo MH.
Fortin JS, et al. Among authors: ganegamage sk.
J Mol Struct. 2022 Nov 5;1267:133574. doi: 10.1016/j.molstruc.2022.133574. Epub 2022 Jun 23.
J Mol Struct. 2022.
PMID: 36310922
Free PMC article.
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Design, synthesis, and evaluation of cystargolide-based β-lactones as potent proteasome inhibitors.
Niroula D, Hallada LP, Le Chapelain C, Ganegamage SK, Dotson D, Rogelj S, Groll M, Tello-Aburto R.
Niroula D, et al. Among authors: ganegamage sk.
Eur J Med Chem. 2018 Sep 5;157:962-977. doi: 10.1016/j.ejmech.2018.08.052. Epub 2018 Aug 20.
Eur J Med Chem. 2018.
PMID: 30165344
Free PMC article.
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