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CDK6 is activated by the atypical cyclin I to promote E2F-mediated gene expression and cancer cell proliferation.
Quandt E, Masip N, Hernández-Ortega S, Sánchez-Botet A, Gasa L, Fernández-Elorduy A, Plutta S, Martínez-Láinez JM, Bru S, Munoz-Torres PM, Floor M, Villà-Freixa J, Morris MC, Vidal A, Villanueva A, Clotet J, Ribeiro MPC. Quandt E, et al. Among authors: villanueva a. Mol Oncol. 2023 Jul;17(7):1228-1245. doi: 10.1002/1878-0261.13438. Epub 2023 May 31. Mol Oncol. 2023. PMID: 37081792 Free PMC article.
Expanding a precision medicine platform for malignant peripheral nerve sheath tumors: New patient-derived orthotopic xenografts, cell lines and tumor entities.
Creus-Bachiller E, Fernández-Rodríguez J, Magallón-Lorenz M, Ortega-Bertran S, Navas-Rutete S, Romagosa C, Silva TM, Pané M, Estival A, Perez Sidelnikova D, Morell M, Mazuelas H, Carrió M, Lausová T, Reuss D, Gel B, Villanueva A, Serra E, Lázaro C. Creus-Bachiller E, et al. Among authors: villanueva a. Mol Oncol. 2024 Apr;18(4):895-917. doi: 10.1002/1878-0261.13534. Epub 2023 Oct 20. Mol Oncol. 2024. PMID: 37798904 Free PMC article.
IκB kinase-α coordinates BRD4 and JAK/STAT signaling to subvert DNA damage-based anticancer therapy.
Pecharromán I, Solé L, Álvarez-Villanueva D, Lobo-Jarne T, Alonso-Marañón J, Bertran J, Guillén Y, Montoto Á, Martínez-Iniesta M, García-Hernández V, Giménez G, Salazar R, Santos C, Garrido M, Borràs E, Sabidó E, Bonfill-Teixidor E, Iurlaro R, Seoane J, Villanueva A, Iglesias M, Bigas A, Espinosa L. Pecharromán I, et al. Among authors: villanueva a. EMBO J. 2023 Nov 2;42(21):e114719. doi: 10.15252/embj.2023114719. Epub 2023 Sep 22. EMBO J. 2023. PMID: 37737566 Free article.
Generation of human iPSC-derived neurofibromaspheres for in vitro and in vivo uses.
Mazuelas H, Uriarte-Arrazola I, Fernández-Rodríguez J, Magallón-Lorenz M, Villanueva A, Lázaro C, Gel B, Serra E, Carrió M. Mazuelas H, et al. Among authors: villanueva a. STAR Protoc. 2023 Mar 27;4(2):102198. doi: 10.1016/j.xpro.2023.102198. Online ahead of print. STAR Protoc. 2023. PMID: 36976677 Free PMC article.
Novel biomarkers and strategies for HCC diagnosis and care.
Wang AE, Leven EA, Grinspan LT, Villanueva A. Wang AE, et al. Among authors: villanueva a. Clin Liver Dis (Hoboken). 2024 May 3;23(1):e0152. doi: 10.1097/CLD.0000000000000152. eCollection 2024 Jan-Jun. Clin Liver Dis (Hoboken). 2024. PMID: 38707238 Free PMC article. Review.
DrugMap: A quantitative pan-cancer analysis of cysteine ligandability.
Takahashi M, Chong HB, Zhang S, Yang TY, Lazarov MJ, Harry S, Maynard M, Hilbert B, White RD, Murrey HE, Tsou CC, Vordermark K, Assaad J, Gohar M, Dürr BR, Richter M, Patel H, Kryukov G, Brooijmans N, Alghali ASO, Rubio K, Villanueva A, Zhang J, Ge M, Makram F, Griesshaber H, Harrison D, Koglin AS, Ojeda S, Karakyriakou B, Healy A, Popoola G, Rachmin I, Khandelwal N, Neil JR, Tien PC, Chen N, Hosp T, van den Ouweland S, Hara T, Bussema L, Dong R, Shi L, Rasmussen MQ, Domingues AC, Lawless A, Fang J, Yoda S, Nguyen LP, Reeves SM, Wakefield FN, Acker A, Clark SE, Dubash T, Kastanos J, Oh E, Fisher DE, Maheswaran S, Haber DA, Boland GM, Sade-Feldman M, Jenkins RW, Hata AN, Bardeesy NM, Suvà ML, Martin BR, Liau BB, Ott CJ, Rivera MN, Lawrence MS, Bar-Peled L. Takahashi M, et al. Among authors: villanueva a. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22. Cell. 2024. PMID: 38653237
898 results