Sulforaphane, an NRF2 agonist, alleviates ferroptosis in acute liver failure by regulating HDAC6 activity.
Zhang YQ, Shi CX, Zhang DM, Zhang LY, Wang LW, Gong ZJ.
Zhang YQ, et al.
J Integr Med. 2023 Sep;21(5):464-473. doi: 10.1016/j.joim.2023.08.002. Epub 2023 Aug 9.
J Integr Med. 2023.
PMID: 37620223
This paper aimed to explore the protective effect of SFN in ALF and it possible mechanisms of action. METHODS: Lipopolysaccharide and D-galactosamine were used to induce liver injury in vitro and in vivo. ...CONCLUSION: SFN has a protective effect on ALF, and the mechanism …
This paper aimed to explore the protective effect of SFN in ALF and it possible mechanisms of action. METHODS: Lipopolysaccharide and D …