Tang G - Search Results

1

2-Ethynylbenzaldehyde-Based, Lysine-Targeting Irreversible Covalent Inhibitors for Protein Kinases and Nonkinases.

Chen P, Tang G, Zhu C, Sun J, Wang X, Xiang M, Huang H, Wang W, Li L, Zhang ZM, Gao L, Yao SQ. Chen P, et al. Among authors: tang g. J Am Chem Soc. 2023 Feb 12. doi: 10.1021/jacs.2c11595. Online ahead of print. J Am Chem Soc. 2023. PMID: 36774655

2

Strategic Design of Catalytic Lysine-Targeting Reversible Covalent BCR-ABL Inhibitors*.

Quach D, Tang G, Anantharajan J, Baburajendran N, Poulsen A, Wee JLK, Retna P, Li R, Liu B, Tee DHY, Kwek PZ, Joy JK, Yang WQ, Zhang CJ, Foo K, Keller TH, Yao SQ. Quach D, et al. Among authors: tang g. Angew Chem Int Ed Engl. 2021 Jul 26;60(31):17131-17137. doi: 10.1002/anie.202105383. Epub 2021 Jun 24. Angew Chem Int Ed Engl. 2021. PMID: 34008286

3

Cell-Penetrating Mitochondrion-Targeting Ligands for the Universal Delivery of Small Molecules, Proteins and Nanomaterials.

Xiao Q, Du W, Dong X, Du S, Ong SY, Tang G, Zhang C, Yang F, Li L, Gao L, Yao SQ. Xiao Q, et al. Among authors: tang g. Chemistry. 2021 Aug 19;27(47):12207-12214. doi: 10.1002/chem.202101989. Epub 2021 Jul 6. Chemistry. 2021. PMID: 34115398

4

Novel Electrophilic Warhead Targeting a Triple-Negative Breast Cancer Driver in Live Cells Revealed by "Inverse Drug Discovery".

Fan Y, Si H, Zhang Z, Zhong L, Sun H, Zhu C, Yin Z, Li H, Tang G, Yao SQ, Sun P, Zhang ZM, Ding K, Li Z. Fan Y, et al. Among authors: tang g. J Med Chem. 2021 Nov 11;64(21):15582-15592. doi: 10.1021/acs.jmedchem.0c02024. Epub 2021 Oct 8. J Med Chem. 2021. PMID: 34623802

5

A targeted covalent inhibitor of p97 with proteome-wide selectivity.

Ye Z, Wang K, Chen L, Jin X, Chen H, Tang G, Yao SQ, Feng Z, Zhang CJ. Ye Z, et al. Among authors: tang g. Acta Pharm Sin B. 2022 Feb;12(2):982-989. doi: 10.1016/j.apsb.2021.09.003. Epub 2021 Sep 8. Acta Pharm Sin B. 2022. PMID: 35256959 Free PMC article.

6

Cell-Active, Reversible, and Irreversible Covalent Inhibitors That Selectively Target the Catalytic Lysine of BCR-ABL Kinase.

Chen P, Sun J, Zhu C, Tang G, Wang W, Xu M, Xiang M, Zhang CJ, Zhang ZM, Gao L, Yao SQ. Chen P, et al. Among authors: tang g. Angew Chem Int Ed Engl. 2022 Jun 27;61(26):e202203878. doi: 10.1002/anie.202203878. Epub 2022 Apr 29. Angew Chem Int Ed Engl. 2022. PMID: 35438229

7

A Late-Stage Aryl C-H Olefination Strategy and Its Application Towards Global Proteome Profiling of Δ⁸ -Tetrahydrocannabinol.

Lim YJ, Tang G, Ye Z, Zhang CJ, Wu J, Yao SQ. Lim YJ, et al. Among authors: tang g. Chemistry. 2023 May 22;29(29):e202300531. doi: 10.1002/chem.202300531. Epub 2023 Apr 5. Chemistry. 2023. PMID: 36920077

8

Orthogonal Strategies for Profiling Potential Cellular Targets of Anandamide and Cannabidiol.

Tang G, Lim YJ, Wang W, Ye Z, Zhang CJ, Yao SQ. Tang G, et al. Chemistry. 2023 Aug 1;29(43):e202300682. doi: 10.1002/chem.202300682. Epub 2023 Jun 30. Chemistry. 2023. PMID: 37265377

9

Cell-active, irreversible covalent inhibitors that selectively target the catalytic lysine of EGFR by using fluorosulfate-based SuFEx chemistry.

Tang G, Wang W, Wang X, Ding K, Ngan SC, Chen JY, Sze SK, Gao L, Yuan P, Lu X, Yao SQ. Tang G, et al. Eur J Med Chem. 2023 Nov 5;259:115671. doi: 10.1016/j.ejmech.2023.115671. Epub 2023 Jul 21. Eur J Med Chem. 2023. PMID: 37499291

10

Multitarget inhibitors/probes that target LRRK2 and AURORA A kinases noncovalently and covalently.

Wang W, Wang X, Tang G, Zhu C, Xiang M, Xiao Q, Zhang ZM, Gao L, Yao SQ. Wang W, et al. Among authors: tang g. Chem Commun (Camb). 2023 Sep 7;59(72):10789-10792. doi: 10.1039/d3cc03530a. Chem Commun (Camb). 2023. PMID: 37594149

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