Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

41 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Results By Year timeline is not available.
Page 1
Discovery of small molecule mechanistic target of rapamycin inhibitors as anti-aging and anti-cancer therapeutics.
Chrienova Z, Rysanek D, Oleksak P, Stary D, Bajda M, Reinis M, Mikyskova R, Novotny O, Andrys R, Skarka A, Vasicova P, Novak J, Valis M, Kuca K, Hodny Z, Nepovimova E. Chrienova Z, et al. Among authors: andrys r. Front Aging Neurosci. 2022 Dec 6;14:1048260. doi: 10.3389/fnagi.2022.1048260. eCollection 2022. Front Aging Neurosci. 2022. PMID: 36561137 Free PMC article.
Pyridinium Oximes with Ortho-Positioned Chlorine Moiety Exhibit Improved Physicochemical Properties and Efficient Reactivation of Human Acetylcholinesterase Inhibited by Several Nerve Agents.
Zorbaz T, Malinak D, Maraković N, Maček Hrvat N, Zandona A, Novotny M, Skarka A, Andrys R, Benkova M, Soukup O, Katalinić M, Kuca K, Kovarik Z, Musilek K. Zorbaz T, et al. Among authors: andrys r. J Med Chem. 2018 Dec 13;61(23):10753-10766. doi: 10.1021/acs.jmedchem.8b01398. Epub 2018 Nov 20. J Med Chem. 2018. PMID: 30383374
Synthesis, in vitro screening and molecular docking of isoquinolinium-5-carbaldoximes as acetylcholinesterase and butyrylcholinesterase reactivators.
Malinak D, Dolezal R, Hepnarova V, Hozova M, Andrys R, Bzonek P, Racakova V, Korabecny J, Gorecki L, Mezeiova E, Psotka M, Jun D, Kuca K, Musilek K. Malinak D, et al. Among authors: andrys r. J Enzyme Inhib Med Chem. 2020 Dec;35(1):478-488. doi: 10.1080/14756366.2019.1710501. J Enzyme Inhib Med Chem. 2020. PMID: 31910701 Free PMC article.
Design, synthesis, and in vitro evaluation of BP-1-102 analogs with modified hydrophobic fragments for STAT3 inhibition.
Oleksak P, Psotka M, Vancurova M, Sapega O, Bieblova J, Reinis M, Rysanek D, Mikyskova R, Chalupova K, Malinak D, Svobodova J, Andrys R, Rehulkova H, Skopek V, Ngoc Lam P, Bartek J, Hodny Z, Musilek K. Oleksak P, et al. Among authors: andrys r. J Enzyme Inhib Med Chem. 2021 Dec;36(1):410-424. doi: 10.1080/14756366.2020.1871336. J Enzyme Inhib Med Chem. 2021. PMID: 33440995 Free PMC article.
Pyridinium-2-carbaldoximes with quinolinium carboxamide moiety are simultaneous reactivators of acetylcholinesterase and butyrylcholinesterase inhibited by nerve agent surrogates.
Lee HM, Andrys R, Jonczyk J, Kim K, Vishakantegowda AG, Malinak D, Skarka A, Schmidt M, Vaskova M, Latka K, Bajda M, Jung YS, Malawska B, Musilek K. Lee HM, et al. Among authors: andrys r. J Enzyme Inhib Med Chem. 2021 Dec;36(1):437-449. doi: 10.1080/14756366.2020.1869954. J Enzyme Inhib Med Chem. 2021. PMID: 33467931 Free PMC article.
Privileged multi-target directed propargyl-tacrines combining cholinesterase and monoamine oxidase inhibition activities.
Chrienova Z, Nepovimova E, Andrys R, Dolezal R, Janockova J, Muckova L, Fabova L, Soukup O, Oleksak P, Valis M, Korabecny J, Marco-Contelles J, Kuca K. Chrienova Z, et al. Among authors: andrys r. J Enzyme Inhib Med Chem. 2022 Dec;37(1):2605-2620. doi: 10.1080/14756366.2022.2122054. J Enzyme Inhib Med Chem. 2022. PMID: 36131624 Free PMC article.
Development of submicromolar 17β-HSD10 inhibitors and their in vitro and in vivo evaluation.
Benek O, Vaskova M, Miskerikova M, Schmidt M, Andrys R, Rotterova A, Skarka A, Hatlapatkova J, Karasova JZ, Medvecky M, Hroch L, Vinklarova L, Fisar Z, Hroudova J, Handl J, Capek J, Rousar T, Kobrlova T, Dolezal R, Soukup O, Aitken L, Gunn-Moore F, Musilek K. Benek O, et al. Among authors: andrys r. Eur J Med Chem. 2023 Oct 5;258:115593. doi: 10.1016/j.ejmech.2023.115593. Epub 2023 Jun 24. Eur J Med Chem. 2023. PMID: 37390508
Frentizole derivatives with mTOR inhibiting and senomorphic properties.
Chrienova Z, Rysanek D, Novak J, Vasicova P, Oleksak P, Andrys R, Skarka A, Dumanovic J, Milovanovic Z, Jacevic V, Chvojkova M, Holubova K, Vales K, Skoupilova V, Valko M, Jomova K, Alomar SY, Botelho FD, Franca TCC, Kuca K, Hodny Z, Nepovimova E. Chrienova Z, et al. Among authors: andrys r. Biomed Pharmacother. 2023 Nov;167:115600. doi: 10.1016/j.biopha.2023.115600. Epub 2023 Sep 30. Biomed Pharmacother. 2023. PMID: 37783152 Free article.
41 results