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The human pathobiont Malassezia furfur secreted protease Mfsap1 regulates cell dispersal and exacerbates skin inflammation.
Goh JPZ, Ruchti F, Poh SE, Koh WLC, Tan KY, Lim YT, Thng STG, Sobota RM, Hoon SS, Liu C, O'Donoghue AJ, LeibundGut-Landmann S, Oon HH, Li H, Dawson TL Jr. Goh JPZ, et al. Among authors: ruchti f. Proc Natl Acad Sci U S A. 2022 Dec 6;119(49):e2212533119. doi: 10.1073/pnas.2212533119. Epub 2022 Nov 29. Proc Natl Acad Sci U S A. 2022. PMID: 36442106 Free PMC article.
The Skin Commensal Yeast Malassezia Triggers a Type 17 Response that Coordinates Anti-fungal Immunity and Exacerbates Skin Inflammation.
Sparber F, De Gregorio C, Steckholzer S, Ferreira FM, Dolowschiak T, Ruchti F, Kirchner FR, Mertens S, Prinz I, Joller N, Buch T, Glatz M, Sallusto F, LeibundGut-Landmann S. Sparber F, et al. Among authors: ruchti f. Cell Host Microbe. 2019 Mar 13;25(3):389-403.e6. doi: 10.1016/j.chom.2019.02.002. Cell Host Microbe. 2019. PMID: 30870621 Free article.
Host Immunity to Malassezia in Health and Disease.
Sparber F, Ruchti F, LeibundGut-Landmann S. Sparber F, et al. Among authors: ruchti f. Front Cell Infect Microbiol. 2020 May 5;10:198. doi: 10.3389/fcimb.2020.00198. eCollection 2020. Front Cell Infect Microbiol. 2020. PMID: 32477963 Free PMC article. Review.
HGT in the human and skin commensal Malassezia: A bacterially derived flavohemoglobin is required for NO resistance and host interaction.
Ianiri G, Coelho MA, Ruchti F, Sparber F, McMahon TJ, Fu C, Bolejack M, Donovan O, Smutney H, Myler P, Dietrich F, Fox D 3rd, LeibundGut-Landmann S, Heitman J. Ianiri G, et al. Among authors: ruchti f. Proc Natl Acad Sci U S A. 2020 Jul 7;117(27):15884-15894. doi: 10.1073/pnas.2003473117. Epub 2020 Jun 23. Proc Natl Acad Sci U S A. 2020. PMID: 32576698 Free PMC article.
Trained immunity and tolerance in innate lymphoid cells, monocytes, and dendritic cells during allergen-specific immunotherapy.
Eljaszewicz A, Ruchti F, Radzikowska U, Globinska A, Boonpiyathad T, Gschwend A, Morita H, Helbling A, Arasi S, Kahlert H, Berek N, Nandy A, Akdis M, Willers C, Moniuszko M, Akdis CA, Sokolowska M. Eljaszewicz A, et al. Among authors: ruchti f. J Allergy Clin Immunol. 2021 May;147(5):1865-1877. doi: 10.1016/j.jaci.2020.08.042. Epub 2020 Oct 9. J Allergy Clin Immunol. 2021. PMID: 33039478 Free article. Clinical Trial.
18 results