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Site-selective photocatalytic functionalization of peptides and proteins at selenocysteine.
Dowman LJ, Kulkarni SS, Alegre-Requena JV, Giltrap AM, Norman AR, Sharma A, Gallegos LC, Mackay AS, Welegedara AP, Watson EE, van Raad D, Niederacher G, Huhmann S, Proschogo N, Patel K, Larance M, Becker CFW, Mackay JP, Lakhwani G, Huber T, Paton RS, Payne RJ. Dowman LJ, et al. Nat Commun. 2022 Nov 12;13(1):6885. doi: 10.1038/s41467-022-34530-z. Nat Commun. 2022. PMID: 36371402 Free PMC article.
Sansanmycin natural product analogues as potent and selective anti-mycobacterials that inhibit lipid I biosynthesis.
Tran AT, Watson EE, Pujari V, Conroy T, Dowman LJ, Giltrap AM, Pang A, Wong WR, Linington RG, Mahapatra S, Saunders J, Charman SA, West NP, Bugg TD, Tod J, Dowson CG, Roper DI, Crick DC, Britton WJ, Payne RJ. Tran AT, et al. Among authors: dowman lj. Nat Commun. 2017 Mar 1;8:14414. doi: 10.1038/ncomms14414. Nat Commun. 2017. PMID: 28248311 Free PMC article.
Chemical Synthesis and Semisynthesis of Lipidated Proteins.
Hanna CC, Kriegesmann J, Dowman LJ, Becker CFW, Payne RJ. Hanna CC, et al. Among authors: dowman lj. Angew Chem Int Ed Engl. 2022 Apr 4;61(15):e202111266. doi: 10.1002/anie.202111266. Epub 2022 Feb 3. Angew Chem Int Ed Engl. 2022. PMID: 34611966 Free PMC article. Review.
Total Synthesis of Glycosylated Human Interferon-γ.
Wang X, Ashhurst AS, Dowman LJ, Watson EE, Li HY, Fairbanks AJ, Larance M, Kwan A, Payne RJ. Wang X, et al. Among authors: dowman lj. Org Lett. 2020 Sep 4;22(17):6863-6867. doi: 10.1021/acs.orglett.0c02401. Epub 2020 Aug 24. Org Lett. 2020. PMID: 32830985
Native Chemical Ligation-Photodesulfurization in Flow.
Chisholm TS, Clayton D, Dowman LJ, Sayers J, Payne RJ. Chisholm TS, et al. Among authors: dowman lj. J Am Chem Soc. 2018 Jul 25;140(29):9020-9024. doi: 10.1021/jacs.8b03115. Epub 2018 May 24. J Am Chem Soc. 2018. PMID: 29792427
Total Synthesis of Teixobactin.
Giltrap AM, Dowman LJ, Nagalingam G, Ochoa JL, Linington RG, Britton WJ, Payne RJ. Giltrap AM, et al. Among authors: dowman lj. Org Lett. 2016 Jun 3;18(11):2788-91. doi: 10.1021/acs.orglett.6b01324. Epub 2016 May 18. Org Lett. 2016. PMID: 27191730
12 results