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Chemical chaperones targeted to the endoplasmic reticulum (ER) and lysosome prevented neurodegeneration in a C9orf72 repeat expansion drosophila amyotrophic lateral sclerosis (ALS) model.
Azoulay-Ginsburg S, Di Salvio M, Weitman M, Afri M, Ribeiro S, Ebbinghaus S, Cestra G, Gruzman A. Azoulay-Ginsburg S, et al. Among authors: ebbinghaus s. Pharmacol Rep. 2021 Apr;73(2):536-550. doi: 10.1007/s43440-021-00226-2. Epub 2021 Mar 4. Pharmacol Rep. 2021. PMID: 33661518
Effects of in vivo conditions on amyloid aggregation.
Owen MC, Gnutt D, Gao M, Wärmländer SKTS, Jarvet J, Gräslund A, Winter R, Ebbinghaus S, Strodel B. Owen MC, et al. Among authors: ebbinghaus s. Chem Soc Rev. 2019 Jul 15;48(14):3946-3996. doi: 10.1039/c8cs00034d. Chem Soc Rev. 2019. PMID: 31192324 Review.
143 results