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Human Primordial Germ Cells Are Specified from Lineage-Primed Progenitors.
Chen D, Sun N, Hou L, Kim R, Faith J, Aslanyan M, Tao Y, Zheng Y, Fu J, Liu W, Kellis M, Clark A. Chen D, et al. Among authors: kellis m. Cell Rep. 2019 Dec 24;29(13):4568-4582.e5. doi: 10.1016/j.celrep.2019.11.083. Cell Rep. 2019. PMID: 31875561 Free PMC article.
Genome-wide In Vivo CNS Screening Identifies Genes that Modify CNS Neuronal Survival and mHTT Toxicity.
Wertz MH, Mitchem MR, Pineda SS, Hachigian LJ, Lee H, Lau V, Powers A, Kulicke R, Madan GK, Colic M, Therrien M, Vernon A, Beja-Glasser VF, Hegde M, Gao F, Kellis M, Hart T, Doench JG, Heiman M. Wertz MH, et al. Among authors: kellis m. Neuron. 2020 Apr 8;106(1):76-89.e8. doi: 10.1016/j.neuron.2020.01.004. Epub 2020 Jan 30. Neuron. 2020. PMID: 32004439 Free PMC article.
Cell Type-Specific Transcriptomics Reveals that Mutant Huntingtin Leads to Mitochondrial RNA Release and Neuronal Innate Immune Activation.
Lee H, Fenster RJ, Pineda SS, Gibbs WS, Mohammadi S, Davila-Velderrain J, Garcia FJ, Therrien M, Novis HS, Gao F, Wilkinson H, Vogt T, Kellis M, LaVoie MJ, Heiman M. Lee H, et al. Among authors: kellis m. Neuron. 2020 Sep 9;107(5):891-908.e8. doi: 10.1016/j.neuron.2020.06.021. Epub 2020 Jul 17. Neuron. 2020. PMID: 32681824 Free PMC article.
Single-cell dissection of the human brain vasculature.
Garcia FJ, Sun N, Lee H, Godlewski B, Mathys H, Galani K, Zhou B, Jiang X, Ng AP, Mantero J, Tsai LH, Bennett DA, Sahin M, Kellis M, Heiman M. Garcia FJ, et al. Among authors: kellis m. Nature. 2022 Mar;603(7903):893-899. doi: 10.1038/s41586-022-04521-7. Epub 2022 Feb 14. Nature. 2022. PMID: 35158371 Free PMC article.
Multitissue H3K27ac profiling of GTEx samples links epigenomic variation to disease.
Hou L, Xiong X, Park Y, Boix C, James B, Sun N, He L, Patel A, Zhang Z, Molinie B, Van Wittenberghe N, Steelman S, Nusbaum C, Aguet F, Ardlie KG, Kellis M. Hou L, et al. Among authors: kellis m. Nat Genet. 2023 Oct;55(10):1665-1676. doi: 10.1038/s41588-023-01509-5. Epub 2023 Sep 28. Nat Genet. 2023. PMID: 37770633 Free PMC article.
Multisensory gamma stimulation promotes glymphatic clearance of amyloid.
Murdock MH, Yang CY, Sun N, Pao PC, Blanco-Duque C, Kahn MC, Kim T, Lavoie NS, Victor MB, Islam MR, Galiana F, Leary N, Wang S, Bubnys A, Ma E, Akay LA, Sneve M, Qian Y, Lai C, McCarthy MM, Kopell N, Kellis M, Piatkevich KD, Boyden ES, Tsai LH. Murdock MH, et al. Among authors: kellis m. Nature. 2024 Mar;627(8002):149-156. doi: 10.1038/s41586-024-07132-6. Epub 2024 Feb 28. Nature. 2024. PMID: 38418876 Free PMC article.
372 results