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Genome-wide analysis of Schistosoma mansoni reveals limited population structure and possible praziquantel drug selection pressure within Ugandan hot-spot communities.
Vianney TJ, Berger DJ, Doyle SR, Sankaranarayanan G, Serubanja J, Nakawungu PK, Besigye F, Sanya RE, Holroyd N, Allan F, Webb EL, Elliott AM, Berriman M, Cotton JA. Vianney TJ, et al. Among authors: cotton ja. PLoS Negl Trop Dis. 2022 Aug 18;16(8):e0010188. doi: 10.1371/journal.pntd.0010188. eCollection 2022 Aug. PLoS Negl Trop Dis. 2022. PMID: 35981002 Free PMC article.
The confounding effects of high genetic diversity on the determination and interpretation of differential gene expression analysis in the parasitic nematode Haemonchus contortus.
Rezansoff AM, Laing R, Martinelli A, Stasiuk S, Redman E, Bartley D, Holroyd N, Devaney E, Sargison ND, Doyle S, Cotton JA, Gilleard JS. Rezansoff AM, et al. Among authors: cotton ja. Int J Parasitol. 2019 Oct;49(11):847-858. doi: 10.1016/j.ijpara.2019.05.012. Epub 2019 Sep 13. Int J Parasitol. 2019. PMID: 31525371 Free article.
Transcriptomic analyses implicate neuronal plasticity and chloride homeostasis in ivermectin resistance and response to treatment in a parasitic nematode.
Laing R, Doyle SR, McIntyre J, Maitland K, Morrison A, Bartley DJ, Kaplan R, Chaudhry U, Sargison N, Tait A, Cotton JA, Britton C, Devaney E. Laing R, et al. Among authors: cotton ja. PLoS Pathog. 2022 Jun 13;18(6):e1010545. doi: 10.1371/journal.ppat.1010545. eCollection 2022 Jun. PLoS Pathog. 2022. PMID: 35696434 Free PMC article.
Genomic landscape of drug response reveals mediators of anthelmintic resistance.
Doyle SR, Laing R, Bartley D, Morrison A, Holroyd N, Maitland K, Antonopoulos A, Chaudhry U, Flis I, Howell S, McIntyre J, Gilleard JS, Tait A, Mable B, Kaplan R, Sargison N, Britton C, Berriman M, Devaney E, Cotton JA. Doyle SR, et al. Among authors: cotton ja. Cell Rep. 2022 Oct 18;41(3):111522. doi: 10.1016/j.celrep.2022.111522. Cell Rep. 2022. PMID: 36261007 Free PMC article.
Population genomic and evolutionary modelling analyses reveal a single major QTL for ivermectin drug resistance in the pathogenic nematode, Haemonchus contortus.
Doyle SR, Illingworth CJR, Laing R, Bartley DJ, Redman E, Martinelli A, Holroyd N, Morrison AA, Rezansoff A, Tracey A, Devaney E, Berriman M, Sargison N, Cotton JA, Gilleard JS. Doyle SR, et al. Among authors: cotton ja. BMC Genomics. 2019 Mar 15;20(1):218. doi: 10.1186/s12864-019-5592-6. BMC Genomics. 2019. PMID: 30876405 Free PMC article.
Genomic and transcriptomic variation defines the chromosome-scale assembly of Haemonchus contortus, a model gastrointestinal worm.
Doyle SR, Tracey A, Laing R, Holroyd N, Bartley D, Bazant W, Beasley H, Beech R, Britton C, Brooks K, Chaudhry U, Maitland K, Martinelli A, Noonan JD, Paulini M, Quail MA, Redman E, Rodgers FH, Sallé G, Shabbir MZ, Sankaranarayanan G, Wit J, Howe KL, Sargison N, Devaney E, Berriman M, Gilleard JS, Cotton JA. Doyle SR, et al. Among authors: cotton ja. Commun Biol. 2020 Nov 9;3(1):656. doi: 10.1038/s42003-020-01377-3. Commun Biol. 2020. PMID: 33168940 Free PMC article.
A Genome Resequencing-Based Genetic Map Reveals the Recombination Landscape of an Outbred Parasitic Nematode in the Presence of Polyploidy and Polyandry.
Doyle SR, Laing R, Bartley DJ, Britton C, Chaudhry U, Gilleard JS, Holroyd N, Mable BK, Maitland K, Morrison AA, Tait A, Tracey A, Berriman M, Devaney E, Cotton JA, Sargison ND. Doyle SR, et al. Among authors: cotton ja. Genome Biol Evol. 2018 Feb 1;10(2):396-409. doi: 10.1093/gbe/evx269. Genome Biol Evol. 2018. PMID: 29267942 Free PMC article.
136 results