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Synthesis of heteroaromatic analogues of (2-aryl-1-cyclopentenyl-1-alkylidene)-(arylmethyloxy)amine COX-2 inhibitors: effects on the inhibitory activity of the replacement of the cyclopentene central core with pyrazole, thiophene or isoxazole ring.
Balsamo A, Coletta I, Guglielmotti A, Landolfi C, Mancini F, Martinelli A, Milanese C, Minutolo F, Nencetti S, Orlandini E, Pinza M, Rapposelli S, Rossello A. Balsamo A, et al. Among authors: nencetti s. Eur J Med Chem. 2003 Feb;38(2):157-68. doi: 10.1016/s0223-5234(02)01448-4. Eur J Med Chem. 2003. PMID: 12620660
Synthesis and 5-HT2A, 5-HT1A and alpha1-binding affinities of 2-[2-Hydroxy-3-(pyridin-3-yl-methyl)amino]-, 2-[2-hydroxy-3-(2-pyridin-2-yl-ethyl)amino]- and 2-[2-hydroxy-3-(4-N-methyl-piperazin-1-yl)-amino]propoxybenzaldehyde-O-(substituted) benzyl oximes.
Orlandini E, Rapposelli S, Nencetti S, Giannaccini G, Betti L, Balsamo A. Orlandini E, et al. Among authors: nencetti s. Arch Pharm (Weinheim). 2007 Mar;340(3):135-9. doi: 10.1002/ardp.200600123. Arch Pharm (Weinheim). 2007. PMID: 17335104
N-O-isopropyl sulfonamido-based hydroxamates: design, synthesis and biological evaluation of selective matrix metalloproteinase-13 inhibitors as potential therapeutic agents for osteoarthritis.
Nuti E, Casalini F, Avramova SI, Santamaria S, Cercignani G, Marinelli L, La Pietra V, Novellino E, Orlandini E, Nencetti S, Tuccinardi T, Martinelli A, Lim NH, Visse R, Nagase H, Rossello A. Nuti E, et al. Among authors: nencetti s. J Med Chem. 2009 Aug 13;52(15):4757-73. doi: 10.1021/jm900261f. J Med Chem. 2009. PMID: 19606871
71 results