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Zn2+-Dependent peptide nucleic acid-based artificial ribonucleases with unprecedented efficiency and specificity.
Chem Commun (Camb). 2021 Oct 19;57(83):10911-10914. doi: 10.1039/d1cc04383h.
Chem Commun (Camb). 2021.
PMID: 34590632
Further Probing of Cu2+-Dependent PNAzymes Acting as Artificial RNA Restriction Enzymes.
Luige O, Murtola M, Ghidini A, Strömberg R.
Luige O, et al.
Molecules. 2019 Feb 14;24(4):672. doi: 10.3390/molecules24040672.
Molecules. 2019.
PMID: 30769777
Free PMC article.
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Innovative developments and emerging technologies in RNA therapeutics.
Halloy F, Biscans A, Bujold KE, Debacker A, Hill AC, Lacroix A, Luige O, Strömberg R, Sundstrom L, Vogel J, Ghidini A.
Halloy F, et al. Among authors: luige o.
RNA Biol. 2022;19(1):313-332. doi: 10.1080/15476286.2022.2027150. Epub 2021 Dec 31.
RNA Biol. 2022.
PMID: 35188077
Free PMC article.
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Influence of sequence variation on the RNA cleavage activity of Zn2+-dimethyl-dppz-PNA-based artificial enzymes.
Luige O, Karalė K, Bose PP, Bollmark M, Tedebark U, Murtola M, Strömberg R.
Luige O, et al.
RSC Adv. 2022 Feb 14;12(9):5398-5406. doi: 10.1039/d1ra08319h. eCollection 2022 Feb 10.
RSC Adv. 2022.
PMID: 35425588
Free PMC article.
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An enhanced biophysical screening strategy to investigate the affinity of ASOs for their target RNA.
Stulz R, Lerche M, Luige O, Taylor A, Geschwindner S, Ghidini A.
Stulz R, et al. Among authors: luige o.
RSC Chem Biol. 2023 Oct 23;4(12):1123-1130. doi: 10.1039/d3cb00072a. eCollection 2023 Nov 29.
RSC Chem Biol. 2023.
PMID: 38033730
Free PMC article.
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Zinc N,N-bis(2-picolyl)amine Chelates Show Substitution-Dependent Cleavage of Phosphodiesters in Models as Well as of PNAzyme-RNA Bulges.
Svenningsen SW, Luige O, Abdulkarim Z, Strömberg R, Williams NH.
Svenningsen SW, et al. Among authors: luige o.
Molecules. 2024 May 3;29(9):2123. doi: 10.3390/molecules29092123.
Molecules. 2024.
PMID: 38731616
Free PMC article.
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