Torres-Santos EC - Search Results

1

Monocyclic Nitro-heteroaryl Nitrones with Dual Mechanism of Activation: Synthesis and Antileishmanial Activity.

Pacheco JDS, Costa DS, Cunha-Júnior EF, Andrade-Neto VV, Fairlamb AH, Wyllie S, Goulart MOF, Santos DC, Silva TL, Alves MA, Costa PRR, Dias AG, Torres-Santos EC. Pacheco JDS, et al. ACS Med Chem Lett. 2021 Aug 16;12(9):1405-1412. doi: 10.1021/acsmedchemlett.1c00193. eCollection 2021 Sep 9. ACS Med Chem Lett. 2021. PMID: 34531949 Free PMC article.

2

Synthesis of chalcone analogues with increased antileishmanial activity.

Boeck P, Bandeira Falcão CA, Leal PC, Yunes RA, Filho VC, Torres-Santos EC, Rossi-Bergmann B. Boeck P, et al. Bioorg Med Chem. 2006 Mar 1;14(5):1538-45. doi: 10.1016/j.bmc.2005.10.005. Epub 2005 Dec 28. Bioorg Med Chem. 2006. PMID: 16386424

3

The pharmacological inhibition of sterol biosynthesis in Leishmania is counteracted by enhancement of LDL endocytosis.

Andrade-Neto VV, Cicco NN, Cunha-Junior EF, Canto-Cavalheiro MM, Atella GC, Torres-Santos EC. Andrade-Neto VV, et al. Acta Trop. 2011 Aug;119(2-3):194-8. doi: 10.1016/j.actatropica.2011.05.001. Epub 2011 May 13. Acta Trop. 2011. PMID: 21601554 Free article.

4

Pterocarpanquinones, aza-pterocarpanquinone and derivatives: synthesis, antineoplasic activity on human malignant cell lines and antileishmanial activity on Leishmania amazonensis.

Buarque CD, Militão GC, Lima DJ, Costa-Lotufo LV, Pessoa C, de Moraes MO, Cunha-Junior EF, Torres-Santos EC, Netto CD, Costa PR. Buarque CD, et al. Bioorg Med Chem. 2011 Nov 15;19(22):6885-91. doi: 10.1016/j.bmc.2011.09.025. Epub 2011 Sep 21. Bioorg Med Chem. 2011. PMID: 22000949 Free article.

5

LDL uptake by Leishmania amazonensis: involvement of membrane lipid microdomains.

De Cicco NN, Pereira MG, Corrêa JR, Andrade-Neto VV, Saraiva FB, Chagas-Lima AC, Gondim KC, Torres-Santos EC, Folly E, Saraiva EM, Cunha-E-Silva NL, Soares MJ, Atella GC. De Cicco NN, et al. Exp Parasitol. 2012 Apr;130(4):330-40. doi: 10.1016/j.exppara.2012.02.014. Epub 2012 Feb 21. Exp Parasitol. 2012. PMID: 22381219 Free article.

6

The stepwise selection for ketoconazole resistance induces upregulation of C14-demethylase (CYP51) in Leishmania amazonensis.

Andrade-Neto VV, Matos-Guedes HL, Gomes DC, Canto-Cavalheiro MM, Rossi-Bergmann B, Torres-Santos EC. Andrade-Neto VV, et al. Mem Inst Oswaldo Cruz. 2012 May;107(3):416-9. doi: 10.1590/s0074-02762012000300018. Mem Inst Oswaldo Cruz. 2012. PMID: 22510839 Free article.

7

LQB-118, an orally active pterocarpanquinone, induces selective oxidative stress and apoptosis in Leishmania amazonensis.

Ribeiro GA, Cunha-Júnior EF, Pinheiro RO, da-Silva SA, Canto-Cavalheiro MM, da Silva AJ, Costa PR, Netto CD, Melo RC, Almeida-Amaral EE, Torres-Santos EC. Ribeiro GA, et al. J Antimicrob Chemother. 2013 Apr;68(4):789-99. doi: 10.1093/jac/dks498. Epub 2013 Jan 3. J Antimicrob Chemother. 2013. PMID: 23288404

8

The new pyrazolyltetrazole derivative MSN20 is effective via oral delivery against cutaneous leishmaniasis.

Faiões Vdos S, Dos Santos MS, Bernardino AM, Cunha-Júnior EF, Canto Cavalheiro MM, Torres-Santos EC. Faiões Vdos S, et al. Antimicrob Agents Chemother. 2014 Oct;58(10):6290-3. doi: 10.1128/AAC.02874-14. Epub 2014 Aug 4. Antimicrob Agents Chemother. 2014. PMID: 25092697 Free PMC article.

9

Pterocarpanquinone LQB-118 induces apoptosis in Leishmania (Viannia) braziliensis and controls lesions in infected hamsters.

Costa L, Pinheiro RO, Dutra PM, Santos RF, Cunha-Júnior EF, Torres-Santos EC, da Silva AJ, Costa PR, Da-Silva SA. Costa L, et al. PLoS One. 2014 Oct 23;9(10):e109672. doi: 10.1371/journal.pone.0109672. eCollection 2014. PLoS One. 2014. PMID: 25340550 Free PMC article.

10

Novel 3,4-methylenedioxyde-6-X-benzaldehyde-thiosemicarbazones: Synthesis and antileishmanial effects against Leishmania amazonensis.

de Melos JL, Torres-Santos EC, Faiões Vdos S, Del Cistia Cde N, Sant'Anna CM, Rodrigues-Santos CE, Echevarria A. de Melos JL, et al. Eur J Med Chem. 2015 Oct 20;103:409-17. doi: 10.1016/j.ejmech.2015.09.009. Epub 2015 Sep 8. Eur J Med Chem. 2015. PMID: 26375353

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