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Suppressor CD4+ T cells expressing HLA-G are expanded in the peripheral blood from patients with acute decompensation of cirrhosis.
Khamri W, Gudd C, Liu T, Nathwani R, Krasniqi M, Azam S, Barbera T, Trovato FM, Possamai L, Triantafyllou E, Seoane RC, Lebosse F, Singanayagam A, Kumar N, Bernsmeier C, Mukherjee S, McPhail M, Weston CJ, Antoniades CG, Thursz MR. Khamri W, et al. Among authors: gudd c. Gut. 2022 Jun;71(6):1192-1202. doi: 10.1136/gutjnl-2021-324071. Epub 2021 Aug 3. Gut. 2022. PMID: 34344786 Free PMC article.
CD8+T cells from patients with cirrhosis display a phenotype that may contribute to cirrhosis-associated immune dysfunction.
Lebossé F, Gudd C, Tunc E, Singanayagam A, Nathwani R, Triantafyllou E, Pop O, Kumar N, Mukherjee S, Hou TZ, Quaglia A, Zoulim F, Wendon J, Dhar A, Thursz M, Antoniades CG, Khamri W. Lebossé F, et al. Among authors: gudd c. EBioMedicine. 2019 Nov;49:258-268. doi: 10.1016/j.ebiom.2019.10.011. Epub 2019 Oct 31. EBioMedicine. 2019. PMID: 31678004 Free PMC article.
PD-1 blockade improves Kupffer cell bacterial clearance in acute liver injury.
Triantafyllou E, Gudd CL, Mawhin MA, Husbyn HC, Trovato FM, Siggins MK, O'Connor T, Kudo H, Mukherjee SK, Wendon JA, Bernsmeier C, Goldin RD, Botto M, Khamri W, McPhail MJ, Possamai LA, Woollard KJ, Antoniades CG, Thursz MR. Triantafyllou E, et al. Among authors: gudd cl. J Clin Invest. 2021 Feb 15;131(4):e140196. doi: 10.1172/JCI140196. J Clin Invest. 2021. PMID: 33320839 Free PMC article.
Activation and transcriptional profile of monocytes and CD8+ T cells are altered in checkpoint inhibitor-related hepatitis.
Gudd CLC, Au L, Triantafyllou E, Shum B, Liu T, Nathwani R, Kumar N, Mukherjee S, Dhar A, Woollard KJ, Yone Y, Pinato DJ, Thursz MR, Goldin RD, Gore ME, Larkin J, Khamri W, Antoniades CG, Turajlic S, Possamai LA. Gudd CLC, et al. J Hepatol. 2021 Jul;75(1):177-189. doi: 10.1016/j.jhep.2021.02.008. Epub 2021 Feb 22. J Hepatol. 2021. PMID: 33631227 Free article.
Immune Checkpoint Inhibitor-Induced Liver Injury.
Gudd CLC, Sheth R, Thursz MR, Triantafyllou E, Possamai LA. Gudd CLC, et al. Semin Liver Dis. 2023 Nov;43(4):402-417. doi: 10.1055/s-0043-1776761. Epub 2023 Dec 15. Semin Liver Dis. 2023. PMID: 38101418 Review.
Proinflammatory CD20+ T cells contribute to CNS-directed autoimmunity.
Ochs J, Nissimov N, Torke S, Freier M, Grondey K, Koch J, Klein M, Feldmann L, Gudd C, Bopp T, Häusser-Kinzel S, Weber MS. Ochs J, et al. Among authors: gudd c. Sci Transl Med. 2022 Mar 30;14(638):eabi4632. doi: 10.1126/scitranslmed.abi4632. Epub 2022 Mar 30. Sci Transl Med. 2022. PMID: 35353539