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The chromatin accessibility landscape reveals distinct transcriptional regulation in the induction of human primordial germ cell-like cells from pluripotent stem cells.
Wang X, Veerapandian V, Yang X, Song K, Xu X, Cui M, Yuan W, Huang Y, Xia X, Yao Z, Wan C, Luo F, Song X, Wang X, Zheng Y, Hutchins AP, Jauch R, Liang M, Wang C, Liu Z, Chang G, Zhao XY. Wang X, et al. Among authors: hutchins ap. Stem Cell Reports. 2021 May 11;16(5):1245-1261. doi: 10.1016/j.stemcr.2021.03.032. Epub 2021 Apr 29. Stem Cell Reports. 2021. PMID: 33930315 Free PMC article.
Transcriptional pause release is a rate-limiting step for somatic cell reprogramming.
Liu L, Xu Y, He M, Zhang M, Cui F, Lu L, Yao M, Tian W, Benda C, Zhuang Q, Huang Z, Li W, Li X, Zhao P, Fan W, Luo Z, Li Y, Wu Y, Hutchins AP, Wang D, Tse HF, Schambach A, Frampton J, Qin B, Bao X, Yao H, Zhang B, Sun H, Pei D, Wang H, Wang J, Esteban MA. Liu L, et al. Among authors: hutchins ap. Cell Stem Cell. 2014 Nov 6;15(5):574-88. doi: 10.1016/j.stem.2014.09.018. Epub 2014 Oct 9. Cell Stem Cell. 2014. PMID: 25312495 Free article.
Transcriptional Control of Somatic Cell Reprogramming.
Xu Y, Zhang M, Li W, Zhu X, Bao X, Qin B, Hutchins AP, Esteban MA. Xu Y, et al. Among authors: hutchins ap. Trends Cell Biol. 2016 Apr;26(4):272-288. doi: 10.1016/j.tcb.2015.12.003. Epub 2016 Jan 15. Trends Cell Biol. 2016. PMID: 26776886 Review.
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