Hoepel W - Search Results

1

Afucosylated IgG characterizes enveloped viral responses and correlates with COVID-19 severity.

Larsen MD, de Graaf EL, Sonneveld ME, Plomp HR, Nouta J, Hoepel W, Chen HJ, Linty F, Visser R, Brinkhaus M, Šuštić T, de Taeye SW, Bentlage AEH, Toivonen S, Koeleman CAM, Sainio S, Kootstra NA, Brouwer PJM, Geyer CE, Derksen NIL, Wolbink G, de Winther M, Sanders RW, van Gils MJ, de Bruin S, Vlaar APJ; Amsterdam UMC COVID-19; biobank study group; Rispens T, den Dunnen J, Zaaijer HL, Wuhrer M, Ellen van der Schoot C, Vidarsson G. Larsen MD, et al. Among authors: hoepel w. Science. 2021 Feb 26;371(6532):eabc8378. doi: 10.1126/science.abc8378. Epub 2020 Dec 23. Science. 2021. PMID: 33361116 Free PMC article.

2

Serum IgA Immune Complexes Promote Proinflammatory Cytokine Production by Human Macrophages, Monocytes, and Kupffer Cells through FcαRI-TLR Cross-Talk.

Hansen IS, Hoepel W, Zaat SAJ, Baeten DLP, den Dunnen J. Hansen IS, et al. Among authors: hoepel w. J Immunol. 2017 Dec 15;199(12):4124-4131. doi: 10.4049/jimmunol.1700883. Epub 2017 Nov 8. J Immunol. 2017. PMID: 29118246

3

FcαRI co-stimulation converts human intestinal CD103⁺ dendritic cells into pro-inflammatory cells through glycolytic reprogramming.

Hansen IS, Krabbendam L, Bernink JH, Loayza-Puch F, Hoepel W, van Burgsteden JA, Kuijper EC, Buskens CJ, Bemelman WA, Zaat SAJ, Agami R, Vidarsson G, van den Brink GR, de Jong EC, Wildenberg ME, Baeten DLP, Everts B, den Dunnen J. Hansen IS, et al. Among authors: hoepel w. Nat Commun. 2018 Feb 28;9(1):863. doi: 10.1038/s41467-018-03318-5. Nat Commun. 2018. PMID: 29491406 Free PMC article.

4

FcγRIII stimulation breaks the tolerance of human nasal epithelial cells to bacteria through cross-talk with TLR4.

Golebski K, Hoepel W, van Egmond D, de Groot EJ, Amatngalim GD, Beekman JM, Fokkens WJ, van Drunen CM, den Dunnen J. Golebski K, et al. Among authors: hoepel w. Mucosal Immunol. 2019 Mar;12(2):425-433. doi: 10.1038/s41385-018-0129-x. Epub 2019 Jan 21. Mucosal Immunol. 2019. PMID: 30664707 Free article.

5

FcγR-TLR Cross-Talk Enhances TNF Production by Human Monocyte-Derived DCs via IRF5-Dependent Gene Transcription and Glycolytic Reprogramming.

Hoepel W, Newling M, Vogelpoel LTC, Sritharan L, Hansen IS, Kapsenberg ML, Baeten DLP, Everts B, den Dunnen J. Hoepel W, et al. Front Immunol. 2019 Apr 8;10:739. doi: 10.3389/fimmu.2019.00739. eCollection 2019. Front Immunol. 2019. PMID: 31024565 Free PMC article.

6

C-Reactive Protein Promotes Inflammation through FcγR-Induced Glycolytic Reprogramming of Human Macrophages.

Newling M, Sritharan L, van der Ham AJ, Hoepel W, Fiechter RH, de Boer L, Zaat SAJ, Bisoendial RJ, Baeten DLP, Everts B, den Dunnen J. Newling M, et al. Among authors: hoepel w. J Immunol. 2019 Jul 1;203(1):225-235. doi: 10.4049/jimmunol.1900172. Epub 2019 May 22. J Immunol. 2019. PMID: 31118224

7

Dysregulated Fcγ receptor IIa-induced cytokine production in dendritic cells of lupus nephritis patients.

Newling M, Fiechter RH, Sritharan L, Hoepel W, van Burgsteden JA, Hak AE, van Vollenhoven RF, van de Sande MGH, Baeten DLP, den Dunnen J. Newling M, et al. Among authors: hoepel w. Clin Exp Immunol. 2020 Jan;199(1):39-49. doi: 10.1111/cei.13371. Epub 2019 Oct 7. Clin Exp Immunol. 2020. PMID: 31509231 Free PMC article. Clinical Trial.

8

Active control of mucosal tolerance and inflammation by human IgA and IgG antibodies.

Hoepel W, Golebski K, van Drunen CM, den Dunnen J. Hoepel W, et al. J Allergy Clin Immunol. 2020 Aug;146(2):273-275. doi: 10.1016/j.jaci.2020.04.032. Epub 2020 May 5. J Allergy Clin Immunol. 2020. PMID: 32387110 No abstract available.

9

IgG Immune Complexes Break Immune Tolerance of Human Microglia.

van der Poel M, Hoepel W, Hamann J, Huitinga I, Dunnen JD. van der Poel M, et al. Among authors: hoepel w. J Immunol. 2020 Nov 1;205(9):2511-2518. doi: 10.4049/jimmunol.2000130. Epub 2020 Sep 23. J Immunol. 2020. PMID: 32967931

10

IgG Subclasses Shape Cytokine Responses by Human Myeloid Immune Cells through Differential Metabolic Reprogramming.

Hoepel W, Allahverdiyeva S, Harbiye H, de Taeye SW, van der Ham AJ, de Boer L, Zaat SAJ, van Weeghel M, Baeten DLP, Houtkooper RH, Everts B, Vidarsson G, den Dunnen J. Hoepel W, et al. J Immunol. 2020 Dec 15;205(12):3400-3407. doi: 10.4049/jimmunol.2000263. Epub 2020 Nov 13. J Immunol. 2020. PMID: 33188071

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