Active control of mucosal tolerance and inflammation by human IgA and IgG antibodies

Willianne Hoepel; Korneliusz Golebski; Cornelis M van Drunen; Jeroen den Dunnen

doi:10.1016/j.jaci.2020.04.032

Active control of mucosal tolerance and inflammation by human IgA and IgG antibodies

J Allergy Clin Immunol. 2020 Aug;146(2):273-275. doi: 10.1016/j.jaci.2020.04.032. Epub 2020 May 5.

Authors

Willianne Hoepel¹, Korneliusz Golebski², Cornelis M van Drunen³, Jeroen den Dunnen⁴

Affiliations

¹ Department of Rheumatology and Clinical Immunology, Academic Medical Center, Amsterdam Rheumatology and Immunology Center, Amsterdam, The Netherlands; Department of Experimental Immunology, Amsterdam Infection and Immunity Institute, Amsterdam, The Netherlands.
² Department of Respiratory Medicine, Amsterdam, The Netherlands.
³ the Department of Otorhinolaryngology, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
⁴ Department of Rheumatology and Clinical Immunology, Academic Medical Center, Amsterdam Rheumatology and Immunology Center, Amsterdam, The Netherlands; Department of Experimental Immunology, Amsterdam Infection and Immunity Institute, Amsterdam, The Netherlands. Electronic address: j.dendunnen@amsterdamumc.nl.

PMID: 32387110
DOI: 10.1016/j.jaci.2020.04.032

No abstract available

Keywords: Fc receptor; allergy; antibodies; chronic rhinosinusitis; dendritic cells; epithelial cells; inflammation; inflammatory bowel disease; tolerance.

Publication types

Editorial

MeSH terms

Animals
Chronic Disease
Dendritic Cells / immunology*
Epithelial Cells / physiology*
Humans
Immune Tolerance
Immunity, Mucosal
Immunoglobulin A / metabolism
Immunoglobulin G / metabolism
Inflammation / immunology*
Inflammatory Bowel Diseases / immunology*
Receptors, Fc / metabolism
Rhinitis / immunology*
Sinusitis / immunology*

Substances

Immunoglobulin A
Immunoglobulin G
Receptors, Fc