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Allosteric inhibitors targeting the calmodulin-PIP2 interface of SK4 K+ channels for atrial fibrillation treatment.
Burg S, Shapiro S, Peretz A, Haimov E, Redko B, Yeheskel A, Simhaev L, Engel H, Raveh A, Ben-Bassat A, Murninkas M, Polak R, Haitin Y, Etzion Y, Attali B. Burg S, et al. Among authors: attali b. Proc Natl Acad Sci U S A. 2022 Aug 23;119(34):e2202926119. doi: 10.1073/pnas.2202926119. Epub 2022 Aug 15. Proc Natl Acad Sci U S A. 2022. PMID: 35969786 Free PMC article.
Ca2+-Calmodulin and PIP2 interactions at the proximal C-terminus of Kv7 channels.
Tobelaim WS, Dvir M, Lebel G, Cui M, Buki T, Peretz A, Marom M, Haitin Y, Logothetis DE, Hirsch JA, Attali B. Tobelaim WS, et al. Among authors: attali b. Channels (Austin). 2017 Nov 2;11(6):686-695. doi: 10.1080/19336950.2017.1388478. Epub 2017 Nov 17. Channels (Austin). 2017. PMID: 28976808 Free PMC article.
An inactivation gate in the selectivity filter of KCNQ1 potassium channels.
Gibor G, Yakubovich D, Rosenhouse-Dantsker A, Peretz A, Schottelndreier H, Seebohm G, Dascal N, Logothetis DE, Paas Y, Attali B. Gibor G, et al. Among authors: attali b. Biophys J. 2007 Dec 15;93(12):4159-72. doi: 10.1529/biophysj.107.107987. Epub 2007 Aug 17. Biophys J. 2007. PMID: 17704175 Free PMC article.
KCNE1 constrains the voltage sensor of Kv7.1 K+ channels.
Shamgar L, Haitin Y, Yisharel I, Malka E, Schottelndreier H, Peretz A, Paas Y, Attali B. Shamgar L, et al. Among authors: attali b. PLoS One. 2008 Apr 9;3(4):e1943. doi: 10.1371/journal.pone.0001943. PLoS One. 2008. PMID: 18398469 Free PMC article.
Channel gating pore: a new therapeutic target.
Kornilov P, Peretz A, Attali B. Kornilov P, et al. Among authors: attali b. Cell Res. 2013 Sep;23(9):1067-8. doi: 10.1038/cr.2013.89. Epub 2013 Jul 9. Cell Res. 2013. PMID: 23835478 Free PMC article.
118 results