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A Chemical Approach for Programmable Protein Outputs Based on Engineered Cell Interactions.
ACS Chem Biol. 2021 Jan 15;16(1):52-57. doi: 10.1021/acschembio.0c00935. Epub 2020 Dec 22.
ACS Chem Biol. 2021.
PMID: 33351606
Free PMC article.
Imaging sensitive and drug-resistant bacterial infection with [11C]-trimethoprim.
Lee IK, Jacome DA, Cho JK, Tu V, Young AJ, Dominguez T, Northrup JD, Etersque JM, Lee HS, Ruff A, Aklilu O, Bittinger K, Glaser LJ, Dorgan D, Hadjiliadis D, Kohli RM, Mach RH, Mankoff DA, Doot RK, Sellmyer MA.
Lee IK, et al. Among authors: jacome da.
J Clin Invest. 2022 Sep 15;132(18):e156679. doi: 10.1172/JCI156679.
J Clin Invest. 2022.
PMID: 36106638
Free PMC article.
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Highly Selective Dopamine D3 Receptor Antagonists with Arylated Diazaspiro Alkane Cores.
Reilly SW, Griffin S, Taylor M, Sahlholm K, Weng CC, Xu K, Jacome DA, Luedtke RR, Mach RH.
Reilly SW, et al. Among authors: jacome da.
J Med Chem. 2017 Dec 14;60(23):9905-9910. doi: 10.1021/acs.jmedchem.7b01248. Epub 2017 Nov 21.
J Med Chem. 2017.
PMID: 29125762
Free PMC article.
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Leveraging a Low-Affinity Diazaspiro Orthosteric Fragment to Reduce Dopamine D3 Receptor (D3R) Ligand Promiscuity across Highly Conserved Aminergic G-Protein-Coupled Receptors (GPCRs).
Reilly SW, Riad AA, Hsieh CJ, Sahlholm K, Jacome DA, Griffin S, Taylor M, Weng CC, Xu K, Kirschner N, Luedtke RR, Parry C, Malhotra S, Karanicolas J, Mach RH.
Reilly SW, et al. Among authors: jacome da.
J Med Chem. 2019 May 23;62(10):5132-5147. doi: 10.1021/acs.jmedchem.9b00412. Epub 2019 May 6.
J Med Chem. 2019.
PMID: 31021617
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