Knez D - Search Results

1

Assessment of Tractable Cysteines for Covalent Targeting by Screening Covalent Fragments.

Petri L, Ábrányi-Balogh P, Tímea I, Pálfy G, Perczel A, Knez D, Hrast M, Gobec M, Sosič I, Nyíri K, Vértessy BG, Jänsch N, Desczyk C, Meyer-Almes FJ, Ogris I, Golič Grdadolnik S, Iacovino LG, Binda C, Gobec S, Keserű GM. Petri L, et al. Among authors: knez d. Chembiochem. 2021 Feb 15;22(4):743-753. doi: 10.1002/cbic.202000700. Epub 2020 Nov 9. Chembiochem. 2021. PMID: 33030752

2

Structure-activity relationships of new cyanothiophene inhibitors of the essential peptidoglycan biosynthesis enzyme MurF.

Hrast M, Turk S, Sosič I, Knez D, Randall CP, Barreteau H, Contreras-Martel C, Dessen A, O'Neill AJ, Mengin-Lecreulx D, Blanot D, Gobec S. Hrast M, et al. Among authors: knez d. Eur J Med Chem. 2013 Aug;66:32-45. doi: 10.1016/j.ejmech.2013.05.013. Epub 2013 May 21. Eur J Med Chem. 2013. PMID: 23786712

3

Design, synthesis and evaluation of second generation MurF inhibitors based on a cyanothiophene scaffold.

Hrast M, Anderluh M, Knez D, Randall CP, Barreteau H, O'Neill AJ, Blanot D, Gobec S. Hrast M, et al. Among authors: knez d. Eur J Med Chem. 2014 Feb 12;73:83-96. doi: 10.1016/j.ejmech.2013.11.031. Epub 2013 Dec 12. Eur J Med Chem. 2014. PMID: 24384549

4

Exploring the aryl esterase catalysis of paraoxonase-1 through solvent kinetic isotope effects and phosphonate-based isosteric analogues of the tetrahedral reaction intermediate.

Bavec A, Knez D, Makovec T, Stojan J, Gobec S, Goličnik M. Bavec A, et al. Among authors: knez d. Biochimie. 2014 Nov;106:184-6. doi: 10.1016/j.biochi.2014.08.011. Epub 2014 Aug 30. Biochimie. 2014. PMID: 25180809

5

Structure-based development of nitroxoline derivatives as potential multifunctional anti-Alzheimer agents.

Knez D, Brus B, Coquelle N, Sosič I, Šink R, Brazzolotto X, Mravljak J, Colletier JP, Gobec S. Knez D, et al. Bioorg Med Chem. 2015 Aug 1;23(15):4442-4452. doi: 10.1016/j.bmc.2015.06.010. Epub 2015 Jun 14. Bioorg Med Chem. 2015. PMID: 26116179

6

LiSiCA: A Software for Ligand-Based Virtual Screening and Its Application for the Discovery of Butyrylcholinesterase Inhibitors.

Lešnik S, Štular T, Brus B, Knez D, Gobec S, Janežič D, Konc J. Lešnik S, et al. Among authors: knez d. J Chem Inf Model. 2015 Aug 24;55(8):1521-8. doi: 10.1021/acs.jcim.5b00136. Epub 2015 Jul 20. J Chem Inf Model. 2015. PMID: 26158767

7

Synthesis and preliminary biological evaluations of (+)-isocampholenic acid-derived amides.

Grošelj U, Golobič A, Knez D, Hrast M, Gobec S, Ričko S, Svete J. Grošelj U, et al. Among authors: knez d. Mol Divers. 2016 Aug;20(3):667-76. doi: 10.1007/s11030-016-9668-9. Epub 2016 Mar 26. Mol Divers. 2016. PMID: 27017352

8

Nonpeptidic Selective Inhibitors of the Chymotrypsin-Like (β5 i) Subunit of the Immunoproteasome.

Sosič I, Gobec M, Brus B, Knez D, Živec M, Konc J, Lešnik S, Ogrizek M, Obreza A, Žigon D, Janežič D, Mlinarič-Raščan I, Gobec S. Sosič I, et al. Among authors: knez d. Angew Chem Int Ed Engl. 2016 May 4;55(19):5745-8. doi: 10.1002/anie.201600190. Epub 2016 Apr 1. Angew Chem Int Ed Engl. 2016. PMID: 27037901

9

Design, synthesis and biological evaluation of new phthalimide and saccharin derivatives with alicyclic amines targeting cholinesterases, beta-secretase and amyloid beta aggregation.

Panek D, Więckowska A, Wichur T, Bajda M, Godyń J, Jończyk J, Mika K, Janockova J, Soukup O, Knez D, Korabecny J, Gobec S, Malawska B. Panek D, et al. Among authors: knez d. Eur J Med Chem. 2017 Jan 5;125:676-695. doi: 10.1016/j.ejmech.2016.09.078. Epub 2016 Sep 26. Eur J Med Chem. 2017. PMID: 27721153

10

Dual inhibitors of cholinesterases and monoamine oxidases for Alzheimer's disease.

Knez D, Sova M, Košak U, Gobec S. Knez D, et al. Future Med Chem. 2017 May;9(8):811-832. doi: 10.4155/fmc-2017-0036. Epub 2017 May 15. Future Med Chem. 2017. PMID: 28504893 Review.

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