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WT1 activates transcription of the splice factor kinase SRPK1 gene in PC3 and K562 cancer cells in the absence of corepressor BASP1.
Belali T, Wodi C, Clark B, Cheung MK, Craig TJ, Wheway G, Wagner N, Wagner KD, Roberts S, Porazinski S, Ladomery M. Belali T, et al. Among authors: cheung mk. Biochim Biophys Acta Gene Regul Mech. 2020 Dec;1863(12):194642. doi: 10.1016/j.bbagrm.2020.194642. Epub 2020 Oct 2. Biochim Biophys Acta Gene Regul Mech. 2020. PMID: 33017668
WT1 mutants reveal SRPK1 to be a downstream angiogenesis target by altering VEGF splicing.
Amin EM, Oltean S, Hua J, Gammons MV, Hamdollah-Zadeh M, Welsh GI, Cheung MK, Ni L, Kase S, Rennel ES, Symonds KE, Nowak DG, Royer-Pokora B, Saleem MA, Hagiwara M, Schumacher VA, Harper SJ, Hinton DR, Bates DO, Ladomery MR. Amin EM, et al. Among authors: cheung mk. Cancer Cell. 2011 Dec 13;20(6):768-80. doi: 10.1016/j.ccr.2011.10.016. Cancer Cell. 2011. PMID: 22172722 Free PMC article.
161 results