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mTORC1 Controls Phase Separation and the Biophysical Properties of the Cytoplasm by Tuning Crowding.
Delarue M, Brittingham GP, Pfeffer S, Surovtsev IV, Pinglay S, Kennedy KJ, Schaffer M, Gutierrez JI, Sang D, Poterewicz G, Chung JK, Plitzko JM, Groves JT, Jacobs-Wagner C, Engel BD, Holt LJ. Delarue M, et al. Among authors: holt lj. Cell. 2018 Jul 12;174(2):338-349.e20. doi: 10.1016/j.cell.2018.05.042. Epub 2018 Jun 21. Cell. 2018. PMID: 29937223 Free PMC article.
Excessive Cell Growth Causes Cytoplasm Dilution And Contributes to Senescence.
Neurohr GE, Terry RL, Lengefeld J, Bonney M, Brittingham GP, Moretto F, Miettinen TP, Vaites LP, Soares LM, Paulo JA, Harper JW, Buratowski S, Manalis S, van Werven FJ, Holt LJ, Amon A. Neurohr GE, et al. Among authors: holt lj. Cell. 2019 Feb 21;176(5):1083-1097.e18. doi: 10.1016/j.cell.2019.01.018. Epub 2019 Feb 7. Cell. 2019. PMID: 30739799 Free PMC article.
Controlling the crowd with a WNK.
Holt LJ, Denes LT. Holt LJ, et al. Cell. 2022 Nov 23;185(24):4465-4467. doi: 10.1016/j.cell.2022.10.027. Cell. 2022. PMID: 36423576 Free PMC article.
Chromosome clustering by Ki-67 excludes cytoplasm during nuclear assembly.
Cuylen-Haering S, Petrovic M, Hernandez-Armendariz A, Schneider MWG, Samwer M, Blaukopf C, Holt LJ, Gerlich DW. Cuylen-Haering S, et al. Among authors: holt lj. Nature. 2020 Nov;587(7833):285-290. doi: 10.1038/s41586-020-2672-3. Epub 2020 Sep 2. Nature. 2020. PMID: 32879492 Free PMC article.
82 results