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Spectroscopic and biochemical characterization of metallo-β-lactamase IMP-1 with dicarboxylic, sulfonyl, and thiol inhibitors.
Zhang H, Yang K, Cheng Z, Thomas C, Steinbrunner A, Pryor C, Vulcan M, Kemp C, Orea D, Paththamperuma C, Chen AY, Cohen SM, Page RC, Tierney DL, Crowder MW. Zhang H, et al. Among authors: yang k. Bioorg Med Chem. 2021 Jun 15;40:116183. doi: 10.1016/j.bmc.2021.116183. Epub 2021 May 1. Bioorg Med Chem. 2021. PMID: 33965839 Free PMC article.
A Single Salt Bridge in VIM-20 Increases Protein Stability and Antibiotic Resistance under Low-Zinc Conditions.
Cheng Z, Shurina BA, Bethel CR, Thomas PW, Marshall SH, Thomas CA, Yang K, Kimble RL, Montgomery JS, Orischak MG, Miller CM, Tennenbaum JL, Nix JC, Tierney DL, Fast W, Bonomo RA, Page RC, Crowder MW. Cheng Z, et al. Among authors: yang k. mBio. 2019 Nov 19;10(6):e02412-19. doi: 10.1128/mBio.02412-19. mBio. 2019. PMID: 31744917 Free PMC article.
Carbapenem Use Is Driving the Evolution of Imipenemase 1 Variants.
Cheng Z, Bethel CR, Thomas PW, Shurina BA, Alao JP, Thomas CA, Yang K, Marshall SH, Zhang H, Sturgill AM, Kravats AN, Page RC, Fast W, Bonomo RA, Crowder MW. Cheng Z, et al. Among authors: yang k. Antimicrob Agents Chemother. 2021 Mar 18;65(4):e01714-20. doi: 10.1128/AAC.01714-20. Print 2021 Mar 18. Antimicrob Agents Chemother. 2021. PMID: 33468463 Free PMC article.
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