Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

407 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Results By Year timeline is not available.
Page 1
TET2 Regulates the Neuroinflammatory Response in Microglia.
Carrillo-Jimenez A, Deniz Ö, Niklison-Chirou MV, Ruiz R, Bezerra-Salomão K, Stratoulias V, Amouroux R, Yip PK, Vilalta A, Cheray M, Scott-Egerton AM, Rivas E, Tayara K, García-Domínguez I, Garcia-Revilla J, Fernandez-Martin JC, Espinosa-Oliva AM, Shen X, St George-Hyslop P, Brown GC, Hajkova P, Joseph B, Venero JL, Branco MR, Burguillos MA. Carrillo-Jimenez A, et al. Cell Rep. 2019 Oct 15;29(3):697-713.e8. doi: 10.1016/j.celrep.2019.09.013. Cell Rep. 2019. PMID: 31618637 Free article.
Does Soluble TREM2 Protect Against Alzheimer's Disease?
Brown GC, St George-Hyslop P. Brown GC, et al. Front Aging Neurosci. 2022 Jan 28;13:834697. doi: 10.3389/fnagi.2021.834697. eCollection 2021. Front Aging Neurosci. 2022. PMID: 35153729 Free PMC article. Review.
Wild-type sTREM2 blocks Aβ aggregation and neurotoxicity, but the Alzheimer's R47H mutant increases Aβ aggregation.
Vilalta A, Zhou Y, Sevalle J, Griffin JK, Satoh K, Allendorf DH, De S, Puigdellívol M, Bruzas A, Burguillos MA, Dodd RB, Chen F, Zhang Y, Flagmeier P, Needham LM, Enomoto M, Qamar S, Henderson J, Walter J, Fraser PE, Klenerman D, Lee SF, St George-Hyslop P, Brown GC. Vilalta A, et al. J Biol Chem. 2021 Jan-Jun;296:100631. doi: 10.1016/j.jbc.2021.100631. Epub 2021 Apr 3. J Biol Chem. 2021. PMID: 33823153 Free PMC article.
TREM2 shedding by cleavage at the H157-S158 bond is accelerated for the Alzheimer's disease-associated H157Y variant.
Thornton P, Sevalle J, Deery MJ, Fraser G, Zhou Y, Ståhl S, Franssen EH, Dodd RB, Qamar S, Gomez Perez-Nievas B, Nicol LS, Eketjäll S, Revell J, Jones C, Billinton A, St George-Hyslop PH, Chessell I, Crowther DC. Thornton P, et al. EMBO Mol Med. 2017 Oct;9(10):1366-1378. doi: 10.15252/emmm.201707673. EMBO Mol Med. 2017. PMID: 28855301 Free PMC article.
407 results