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Adjuvanticity of the oil-in-water emulsion MF59 is independent of Nlrp3 inflammasome but requires the adaptor protein MyD88.
Seubert A, Calabro S, Santini L, Galli B, Genovese A, Valentini S, Aprea S, Colaprico A, D'Oro U, Giuliani MM, Pallaoro M, Pizza M, O'Hagan DT, Wack A, Rappuoli R, De Gregorio E. Seubert A, et al. Proc Natl Acad Sci U S A. 2011 Jul 5;108(27):11169-74. doi: 10.1073/pnas.1107941108. Epub 2011 Jun 20. Proc Natl Acad Sci U S A. 2011. PMID: 21690334 Free PMC article.
The Human Pathogen Streptococcus pyogenes Releases Lipoproteins as Lipoprotein-rich Membrane Vesicles.
Biagini M, Garibaldi M, Aprea S, Pezzicoli A, Doro F, Becherelli M, Taddei AR, Tani C, Tavarini S, Mora M, Teti G, D'Oro U, Nuti S, Soriani M, Margarit I, Rappuoli R, Grandi G, Norais N. Biagini M, et al. Mol Cell Proteomics. 2015 Aug;14(8):2138-49. doi: 10.1074/mcp.M114.045880. Epub 2015 May 27. Mol Cell Proteomics. 2015. PMID: 26018414 Free PMC article.
Adjuvant effect of TLR7 agonist adsorbed on aluminum hydroxide (AS37): A phase I randomized, dose escalation study of an AS37-adjuvanted meningococcal C conjugated vaccine.
Gonzalez-Lopez A, Oostendorp J, Koernicke T, Fadini T, D'Oro U, Baker S, O'Hagan DT, Del Giudice G, Siena E, Finco O, Medini D. Gonzalez-Lopez A, et al. Clin Immunol. 2019 Dec;209:108275. doi: 10.1016/j.clim.2019.108275. Epub 2019 Oct 24. Clin Immunol. 2019. PMID: 31669193 Free article. Clinical Trial.
Serafino Zappacosta: An Enlightened Mentor and Educator.
Carbone E, De Felice M, Di Rosa F, D'Oro U, Fontana S, La Cava A, Maio M, Matarese G, Racioppi L, Ruggiero G, Terrazzano G. Carbone E, et al. Among authors: d oro u. Front Immunol. 2020 Feb 13;11:217. doi: 10.3389/fimmu.2020.00217. eCollection 2020. Front Immunol. 2020. PMID: 32117323 Free PMC article.
61 results