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Safety pharmacology methods and regulatory considerations evolve together.
Pugsley MK, Harter ML, de Korte T, Connaughton C, Authier S, Curtis MJ. Pugsley MK, et al. Among authors: de korte t. J Pharmacol Toxicol Methods. 2018 Sep-Oct;93:1-6. doi: 10.1016/j.vascn.2018.06.004. Epub 2018 Jun 21. J Pharmacol Toxicol Methods. 2018. PMID: 29936032 No abstract available.
Safety pharmacology during the COVID pandemic.
Pugsley MK, Koshman Y, de Korte T, Authier S, Curtis MJ. Pugsley MK, et al. Among authors: de korte t. J Pharmacol Toxicol Methods. 2021 Sep-Oct;111:107089. doi: 10.1016/j.vascn.2021.107089. Epub 2021 Jun 26. J Pharmacol Toxicol Methods. 2021. PMID: 34182120 Free PMC article.
Predicting cardiac safety using human induced pluripotent stem cell-derived cardiomyocytes combined with multi-electrode array (MEA) technology: A conference report.
Mulder P, de Korte T, Dragicevic E, Kraushaar U, Printemps R, Vlaming MLH, Braam SR, Valentin JP. Mulder P, et al. Among authors: de korte t. J Pharmacol Toxicol Methods. 2018 May-Jun;91:36-42. doi: 10.1016/j.vascn.2018.01.003. Epub 2018 Feb 4. J Pharmacol Toxicol Methods. 2018. PMID: 29355722
[No title available]
[No authors listed] [No authors listed] PMID: 31962931
Blinded, Multicenter Evaluation of Drug-induced Changes in Contractility Using Human-induced Pluripotent Stem Cell-derived Cardiomyocytes.
Saleem U, van Meer BJ, Katili PA, Mohd Yusof NAN, Mannhardt I, Garcia AK, Tertoolen L, de Korte T, Vlaming MLH, McGlynn K, Nebel J, Bahinski A, Harris K, Rossman E, Xu X, Burton FL, Smith GL, Clements P, Mummery CL, Eschenhagen T, Hansen A, Denning C. Saleem U, et al. Among authors: de korte t. Toxicol Sci. 2020 Jul 1;176(1):103-123. doi: 10.1093/toxsci/kfaa058. Toxicol Sci. 2020. PMID: 32421822 Free PMC article.
Unlocking Personalized Biomedicine and Drug Discovery with Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes: Fit for Purpose or Forever Elusive?
de Korte T, Katili PA, Mohd Yusof NAN, van Meer BJ, Saleem U, Burton FL, Smith GL, Clements P, Mummery CL, Eschenhagen T, Hansen A, Denning C. de Korte T, et al. Annu Rev Pharmacol Toxicol. 2020 Jan 6;60:529-551. doi: 10.1146/annurev-pharmtox-010919-023309. Epub 2019 Sep 10. Annu Rev Pharmacol Toxicol. 2020. PMID: 31506008 Review.
17 results