Safety pharmacology methods and regulatory considerations evolve together

J Pharmacol Toxicol Methods. 2018 Sep-Oct:93:1-6. doi: 10.1016/j.vascn.2018.06.004. Epub 2018 Jun 21.

Authors

Michael K Pugsley¹, Marci L Harter², Tessa de Korte³, Chantelle Connaughton⁴, Simon Authier⁵, Michael J Curtis⁶

Affiliations

¹ CiToxLAB Research Inc., Laval, QC H7V 4B3, Canada. Electronic address: mkpugsley@yahoo.com.
² Safety Pharmacology, MPI Research, Mattawan, MI, United States.
³ Ncardia, Leiden 2333, BD, the Netherlands.
⁴ Mundipharma Research Ltd., Cambridge CB4 0GW, UK.
⁵ CiToxLAB Research Inc., Laval, QC H7V 4B3, Canada.
⁶ Cardiovascular Division, Rayne Institute, St Thomas' Hospital, London SE17EH, UK.

PMID: 29936032
DOI: 10.1016/j.vascn.2018.06.004

No abstract available

Publication types

Congress
Editorial
Introductory Journal Article

MeSH terms

Animals
Cardiology / methods
Drug Evaluation, Preclinical / methods*
Drug Evaluation, Preclinical / standards
Drug and Narcotic Control / methods
Drug-Related Side Effects and Adverse Reactions / prevention & control
Humans
Pharmacology / methods*
Pharmacology / standards
Safety