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The 17,18-epoxyeicosatetraenoic acid-G protein-coupled receptor 40 axis ameliorates contact hypersensitivity by inhibiting neutrophil mobility in mice and cynomolgus macaques.
Nagatake T, Shiogama Y, Inoue A, Kikuta J, Honda T, Tiwari P, Kishi T, Yanagisawa A, Isobe Y, Matsumoto N, Shimojou M, Morimoto S, Suzuki H, Hirata SI, Steneberg P, Edlund H, Aoki J, Arita M, Kiyono H, Yasutomi Y, Ishii M, Kabashima K, Kunisawa J. Nagatake T, et al. Among authors: morimoto s. J Allergy Clin Immunol. 2018 Aug;142(2):470-484.e12. doi: 10.1016/j.jaci.2017.09.053. Epub 2017 Dec 27. J Allergy Clin Immunol. 2018. PMID: 29288079 Free article.
ω3 fatty acid metabolite, 12-hydroxyeicosapentaenoic acid, alleviates contact hypersensitivity by downregulation of CXCL1 and CXCL2 gene expression in keratinocytes via retinoid X receptor α.
Saika A, Nagatake T, Hirata SI, Sawane K, Adachi J, Abe Y, Isoyama J, Morimoto S, Node E, Tiwari P, Hosomi K, Matsunaga A, Honda T, Tomonaga T, Arita M, Kabashima K, Kunisawa J. Saika A, et al. Among authors: morimoto s. FASEB J. 2021 Apr;35(4):e21354. doi: 10.1096/fj.202001687R. FASEB J. 2021. PMID: 33749892
17(S),18(R)-epoxyeicosatetraenoic acid generated by cytochrome P450 BM-3 from Bacillus megaterium inhibits the development of contact hypersensitivity via G-protein-coupled receptor 40-mediated neutrophil suppression.
Saika A, Nagatake T, Kishino S, Park SB, Honda T, Matsumoto N, Shimojou M, Morimoto S, Tiwari P, Node E, Hirata SI, Hosomi K, Kabashima K, Ogawa J, Kunisawa J. Saika A, et al. Among authors: morimoto s. FASEB Bioadv. 2019 Dec 24;2(1):59-71. doi: 10.1096/fba.2019-00061. eCollection 2020 Jan. FASEB Bioadv. 2019. PMID: 32123857 Free PMC article.
Intestinal microbe-dependent ω3 lipid metabolite αKetoA prevents inflammatory diseases in mice and cynomolgus macaques.
Nagatake T, Kishino S, Urano E, Murakami H, Kitamura N, Konishi K, Ohno H, Tiwari P, Morimoto S, Node E, Adachi J, Abe Y, Isoyama J, Sawane K, Honda T, Inoue A, Uwamizu A, Matsuzaka T, Miyamoto Y, Hirata SI, Saika A, Shibata Y, Hosomi K, Matsunaga A, Shimano H, Arita M, Aoki J, Oka M, Matsutani A, Tomonaga T, Kabashima K, Miyachi M, Yasutomi Y, Ogawa J, Kunisawa J. Nagatake T, et al. Among authors: morimoto s. Mucosal Immunol. 2022 Feb;15(2):289-300. doi: 10.1038/s41385-021-00477-5. Epub 2022 Jan 10. Mucosal Immunol. 2022. PMID: 35013573 Free PMC article.
BLT1 mediates commensal bacteria-dependent innate immune signals to enhance antigen-specific intestinal IgA responses.
Nagatake T, Hirata SI, Koga T, Kuroda E, Kobari S, Suzuki H, Hosomi K, Matsumoto N, Yanrismet Y, Shimojou M, Morimoto S, Sasaki F, Ishii KJ, Yokomizo T, Kunisawa J. Nagatake T, et al. Among authors: morimoto s. Mucosal Immunol. 2019 Sep;12(5):1082-1091. doi: 10.1038/s41385-019-0175-z. Epub 2019 May 29. Mucosal Immunol. 2019. PMID: 31142830 Free article.
Immunological association of inducible bronchus-associated lymphoid tissue organogenesis in Ag85B-rHPIV2 vaccine-induced anti-tuberculosis mucosal immune responses in mice.
Nagatake T, Suzuki H, Hirata SI, Matsumoto N, Wada Y, Morimoto S, Nasu A, Shimojou M, Kawano M, Ogami K, Tsujimura Y, Kuroda E, Iijima N, Hosomi K, Ishii KJ, Nosaka T, Yasutomi Y, Kunisawa J. Nagatake T, et al. Among authors: morimoto s. Int Immunol. 2018 Sep 25;30(10):471-481. doi: 10.1093/intimm/dxy046. Int Immunol. 2018. PMID: 30011025 Free PMC article.
Aberrant CHCHD2-associated mitochondriopathy in Kii ALS/PDC astrocytes.
Leventoux N, Morimoto S, Ishikawa M, Nakamura S, Ozawa F, Kobayashi R, Watanabe H, Supakul S, Okamoto S, Zhou Z, Kobayashi H, Kato C, Hirokawa Y, Aiba I, Takahashi S, Shibata S, Takao M, Yoshida M, Endo F, Yamanaka K, Kokubo Y, Okano H. Leventoux N, et al. Among authors: morimoto s. Acta Neuropathol. 2024 May 15;147(1):84. doi: 10.1007/s00401-024-02734-w. Acta Neuropathol. 2024. PMID: 38750212
2,085 results