Jackson CJ - Search Results

1

Cryptic genetic variation shapes the adaptive evolutionary potential of enzymes.

Baier F, Hong N, Yang G, Pabis A, Miton CM, Barrozo A, Carr PD, Kamerlin SC, Jackson CJ, Tokuriki N. Baier F, et al. Among authors: jackson cj. Elife. 2019 Feb 5;8:e40789. doi: 10.7554/eLife.40789. Elife. 2019. PMID: 30719972 Free PMC article.

2

The structure of an enzyme-product complex reveals the critical role of a terminal hydroxide nucleophile in the bacterial phosphotriesterase mechanism.

Jackson C, Kim HK, Carr PD, Liu JW, Ollis DL. Jackson C, et al. Biochim Biophys Acta. 2005 Aug 31;1752(1):56-64. doi: 10.1016/j.bbapap.2005.06.008. Biochim Biophys Acta. 2005. PMID: 16054447

3

Anomalous scattering analysis of Agrobacterium radiobacter phosphotriesterase: the prominent role of iron in the heterobinuclear active site.

Jackson CJ, Carr PD, Kim HK, Liu JW, Herrald P, Mitić N, Schenk G, Smith CA, Ollis DL. Jackson CJ, et al. Biochem J. 2006 Aug 1;397(3):501-8. doi: 10.1042/BJ20060276. Biochem J. 2006. PMID: 16686603 Free PMC article.

4

The purification, crystallization and preliminary diffraction of a glycerophosphodiesterase from Enterobacter aerogenes.

Jackson CJ, Carr PD, Kim HK, Liu JW, Ollis DL. Jackson CJ, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Jul 1;62(Pt 7):659-61. doi: 10.1107/S1744309106020021. Epub 2006 Jun 10. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006. PMID: 16820687 Free PMC article.

5

The structure and function of a novel glycerophosphodiesterase from Enterobacter aerogenes.

Jackson CJ, Carr PD, Liu JW, Watt SJ, Beck JL, Ollis DL. Jackson CJ, et al. J Mol Biol. 2007 Apr 6;367(4):1047-62. doi: 10.1016/j.jmb.2007.01.032. Epub 2007 Jan 20. J Mol Biol. 2007. PMID: 17306828

6

In crystallo capture of a Michaelis complex and product-binding modes of a bacterial phosphotriesterase.

Jackson CJ, Foo JL, Kim HK, Carr PD, Liu JW, Salem G, Ollis DL. Jackson CJ, et al. J Mol Biol. 2008 Feb 1;375(5):1189-96. doi: 10.1016/j.jmb.2007.10.061. Epub 2007 Nov 1. J Mol Biol. 2008. PMID: 18082180

7

Malonate-bound structure of the glycerophosphodiesterase from Enterobacter aerogenes (GpdQ) and characterization of the native Fe2+ metal-ion preference.

Jackson CJ, Hadler KS, Carr PD, Oakley AJ, Yip S, Schenk G, Ollis DL. Jackson CJ, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008 Aug 1;64(Pt 8):681-5. doi: 10.1107/S1744309108017600. Epub 2008 Jul 5. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008. PMID: 18678932 Free PMC article.

8

Substrate-promoted formation of a catalytically competent binuclear center and regulation of reactivity in a glycerophosphodiesterase from Enterobacter aerogenes.

Hadler KS, Tanifum EA, Yip SH, Mitić N, Guddat LW, Jackson CJ, Gahan LR, Nguyen K, Carr PD, Ollis DL, Hengge AC, Larrabee JA, Schenk G. Hadler KS, et al. Among authors: jackson cj. J Am Chem Soc. 2008 Oct 29;130(43):14129-38. doi: 10.1021/ja803346w. Epub 2008 Oct 3. J Am Chem Soc. 2008. PMID: 18831553 Free PMC article.

9

Conformational sampling, catalysis, and evolution of the bacterial phosphotriesterase.

Jackson CJ, Foo JL, Tokuriki N, Afriat L, Carr PD, Kim HK, Schenk G, Tawfik DS, Ollis DL. Jackson CJ, et al. Proc Natl Acad Sci U S A. 2009 Dec 22;106(51):21631-6. doi: 10.1073/pnas.0907548106. Epub 2009 Dec 4. Proc Natl Acad Sci U S A. 2009. PMID: 19966226 Free PMC article.

10

Mutation of outer-shell residues modulates metal ion co-ordination strength in a metalloenzyme.

Foo JL, Jackson CJ, Carr PD, Kim HK, Schenk G, Gahan LR, Ollis DL. Foo JL, et al. Among authors: jackson cj. Biochem J. 2010 Jul 15;429(2):313-21. doi: 10.1042/BJ20100233. Biochem J. 2010. PMID: 20459397

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