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New tetrahydroisoquinoline-based P-glycoprotein modulators: decoration of the biphenyl core gives selective ligands.
Contino M, Guglielmo S, Perrone MG, Giampietro R, Rolando B, Carrieri A, Zaccaria D, Chegaev K, Borio V, Riganti C, Zabielska-Koczywąs K, Colabufo NA, Fruttero R. Contino M, et al. Among authors: carrieri a. Medchemcomm. 2018 Apr 3;9(5):862-869. doi: 10.1039/c8md00075a. eCollection 2018 May 1. Medchemcomm. 2018. PMID: 30108975 Free PMC article.
Structure-Activity Relationship Studies on Tetrahydroisoquinoline Derivatives: [4'-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-ylmethyl)biphenyl-4-ol] (MC70) Conjugated through Flexible Alkyl Chains with Furazan Moieties Gives Rise to Potent and Selective Ligands of P-glycoprotein.
Guglielmo S, Lazzarato L, Contino M, Perrone MG, Chegaev K, Carrieri A, Fruttero R, Colabufo NA, Gasco A. Guglielmo S, et al. Among authors: carrieri a. J Med Chem. 2016 Jul 28;59(14):6729-38. doi: 10.1021/acs.jmedchem.6b00252. Epub 2016 Jul 7. J Med Chem. 2016. PMID: 27336199
Bioisosteric Modification of To042: Synthesis and Evaluation of Promising Use-Dependent Inhibitors of Voltage-Gated Sodium Channels.
Milani G, Cavalluzzi MM, Altamura C, Santoro A, Perrone M, Muraglia M, Colabufo NA, Corbo F, Casalino E, Franchini C, Pisano I, Desaphy JF, Carrieri A, Carocci A, Lentini G. Milani G, et al. Among authors: carrieri a. ChemMedChem. 2021 Dec 6;16(23):3588-3599. doi: 10.1002/cmdc.202100496. Epub 2021 Oct 5. ChemMedChem. 2021. PMID: 34519427 Free PMC article.
Nature-Inspired 1-Phenylpyrrolo[2,1-a]isoquinoline Scaffold for Novel Antiproliferative Agents Circumventing P-Glycoprotein-Dependent Multidrug Resistance.
Nevskaya AA, Purgatorio R, Borisova TN, Varlamov AV, Anikina LV, Obydennik AY, Nevskaya EY, Niso M, Colabufo NA, Carrieri A, Catto M, de Candia M, Voskressensky LG, Altomare CD. Nevskaya AA, et al. Among authors: carrieri a. Pharmaceuticals (Basel). 2024 Apr 22;17(4):539. doi: 10.3390/ph17040539. Pharmaceuticals (Basel). 2024. PMID: 38675499 Free PMC article.
2-Aminobenzothiazole derivatives: search for new antifungal agents.
Catalano A, Carocci A, Defrenza I, Muraglia M, Carrieri A, Van Bambeke F, Rosato A, Corbo F, Franchini C. Catalano A, et al. Among authors: carrieri a. Eur J Med Chem. 2013 Jun;64:357-64. doi: 10.1016/j.ejmech.2013.03.064. Epub 2013 Apr 9. Eur J Med Chem. 2013. PMID: 23644218 Free article.
149 results