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Ligand-Enabled β-C(sp3)-H Olefination of Free Carboxylic Acids.
Zhuang Z, Yu CB, Chen G, Wu QF, Hsiao Y, Joe CL, Qiao JX, Poss MA, Yu JQ. Zhuang Z, et al. Among authors: qiao jx. J Am Chem Soc. 2018 Aug 15;140(32):10363-10367. doi: 10.1021/jacs.8b06527. Epub 2018 Aug 2. J Am Chem Soc. 2018. PMID: 30029574 Free PMC article.
Diphenylpyridylethanamine (DPPE) derivatives as cholesteryl ester transfer protein (CETP) inhibitors.
Harikrishnan LS, Finlay HJ, Qiao JX, Kamau MG, Jiang J, Wang TC, Li J, Cooper CB, Poss MA, Adam LP, Taylor DS, Chen AY, Yin X, Sleph PG, Yang RZ, Sitkoff DF, Galella MA, Nirschl DS, Van Kirk K, Miller AV, Huang CS, Chang M, Chen XQ, Salvati ME, Wexler RR, Lawrence RM. Harikrishnan LS, et al. Among authors: qiao jx. J Med Chem. 2012 Jul 12;55(13):6162-75. doi: 10.1021/jm300611v. Epub 2012 Jun 22. J Med Chem. 2012. PMID: 22650305
Triphenylethanamine Derivatives as Cholesteryl Ester Transfer Protein Inhibitors: Discovery of N-[(1R)-1-(3-Cyclopropoxy-4-fluorophenyl)-1-[3-fluoro-5-(1,1,2,2-tetrafluoroethoxy)phenyl]-2-phenylethyl]-4-fluoro-3-(trifluoromethyl)benzamide (BMS-795311).
Qiao JX, Wang TC, Adam LP, Chen AY, Taylor DS, Yang RZ, Zhuang S, Sleph PG, Li JP, Li D, Yin X, Chang M, Chen XQ, Shen H, Li J, Smith D, Wu DR, Leith L, Harikrishnan LS, Kamau MG, Miller MM, Bilder D, Rampulla R, Li YX, Xu C, Lawrence RM, Poss MA, Levesque P, Gordon DA, Huang CS, Finlay HJ, Wexler RR, Salvati ME. Qiao JX, et al. J Med Chem. 2015 Nov 25;58(22):9010-26. doi: 10.1021/acs.jmedchem.5b01363. Epub 2015 Nov 17. J Med Chem. 2015. PMID: 26524347
Decarboxylative Peptide Macrocyclization through Photoredox Catalysis.
McCarver SJ, Qiao JX, Carpenter J, Borzilleri RM, Poss MA, Eastgate MD, Miller MM, MacMillan DW. McCarver SJ, et al. Among authors: qiao jx. Angew Chem Int Ed Engl. 2017 Jan 16;56(3):728-732. doi: 10.1002/anie.201608207. Epub 2016 Nov 17. Angew Chem Int Ed Engl. 2017. PMID: 27860140 Free PMC article.
CITU: A Peptide and Decarboxylative Coupling Reagent.
deGruyter JN, Malins LR, Wimmer L, Clay KJ, Lopez-Ogalla J, Qin T, Cornella J, Liu Z, Che G, Bao D, Stevens JM, Qiao JX, Allen MP, Poss MA, Baran PS. deGruyter JN, et al. Among authors: qiao jx. Org Lett. 2017 Nov 17;19(22):6196-6199. doi: 10.1021/acs.orglett.7b03121. Epub 2017 Nov 8. Org Lett. 2017. PMID: 29115835 Free PMC article.
Ligand-accelerated non-directed C-H functionalization of arenes.
Wang P, Verma P, Xia G, Shi J, Qiao JX, Tao S, Cheng PTW, Poss MA, Farmer ME, Yeung KS, Yu JQ. Wang P, et al. Among authors: qiao jx. Nature. 2017 Nov 22;551(7681):489-493. doi: 10.1038/nature24632. Nature. 2017. PMID: 29168802 Free PMC article.
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