Vries R - Search Results

1

Lipid-mediated Wnt protein stabilization enables serum-free culture of human organ stem cells.

Tüysüz N, van Bloois L, van den Brink S, Begthel H, Verstegen MM, Cruz LJ, Hui L, van der Laan LJ, de Jonge J, Vries R, Braakman E, Mastrobattista E, Cornelissen JJ, Clevers H, Ten Berge D. Tüysüz N, et al. Among authors: vries r. Nat Commun. 2017 Mar 6;8:14578. doi: 10.1038/ncomms14578. Nat Commun. 2017. PMID: 28262686 Free PMC article.

2

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche.

Sato T, Vries RG, Snippert HJ, van de Wetering M, Barker N, Stange DE, van Es JH, Abo A, Kujala P, Peters PJ, Clevers H. Sato T, et al. Nature. 2009 May 14;459(7244):262-5. doi: 10.1038/nature07935. Epub 2009 Mar 29. Nature. 2009. PMID: 19329995

3

The kinase TNIK is an essential activator of Wnt target genes.

Mahmoudi T, Li VS, Ng SS, Taouatas N, Vries RG, Mohammed S, Heck AJ, Clevers H. Mahmoudi T, et al. EMBO J. 2009 Nov 4;28(21):3329-40. doi: 10.1038/emboj.2009.285. Epub 2009 Oct 8. EMBO J. 2009. PMID: 19816403 Free PMC article.

4

Lgr6 marks stem cells in the hair follicle that generate all cell lineages of the skin.

Snippert HJ, Haegebarth A, Kasper M, Jaks V, van Es JH, Barker N, van de Wetering M, van den Born M, Begthel H, Vries RG, Stange DE, Toftgård R, Clevers H. Snippert HJ, et al. Among authors: vries rg. Science. 2010 Mar 12;327(5971):1385-9. doi: 10.1126/science.1184733. Science. 2010. PMID: 20223988

5

Stem cells and cancer of the stomach and intestine.

Vries RG, Huch M, Clevers H. Vries RG, et al. Mol Oncol. 2010 Oct;4(5):373-84. doi: 10.1016/j.molonc.2010.05.001. Epub 2010 Jun 8. Mol Oncol. 2010. PMID: 20598659 Free PMC article. Review.

6

The leukemia-associated Mllt10/Af10-Dot1l are Tcf4/β-catenin coactivators essential for intestinal homeostasis.

Mahmoudi T, Boj SF, Hatzis P, Li VS, Taouatas N, Vries RG, Teunissen H, Begthel H, Korving J, Mohammed S, Heck AJ, Clevers H. Mahmoudi T, et al. Among authors: vries rg. PLoS Biol. 2010 Nov 16;8(11):e1000539. doi: 10.1371/journal.pbio.1000539. PLoS Biol. 2010. PMID: 21103407 Free PMC article.

7

Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts.

Sato T, van Es JH, Snippert HJ, Stange DE, Vries RG, van den Born M, Barker N, Shroyer NF, van de Wetering M, Clevers H. Sato T, et al. Nature. 2011 Jan 20;469(7330):415-8. doi: 10.1038/nature09637. Epub 2010 Nov 28. Nature. 2011. PMID: 21113151 Free PMC article.

8

Lgr5 intestinal stem cells have high telomerase activity and randomly segregate their chromosomes.

Schepers AG, Vries R, van den Born M, van de Wetering M, Clevers H. Schepers AG, et al. Among authors: vries r. EMBO J. 2011 Mar 16;30(6):1104-9. doi: 10.1038/emboj.2011.26. Epub 2011 Feb 4. EMBO J. 2011. PMID: 21297579 Free PMC article.

9

Differentiated human colorectal cancer cells protect tumor-initiating cells from irinotecan.

Emmink BL, Van Houdt WJ, Vries RG, Hoogwater FJ, Govaert KM, Verheem A, Nijkamp MW, Steller EJ, Jimenez CR, Clevers H, Borel Rinkes IH, Kranenburg O. Emmink BL, et al. Among authors: vries rg. Gastroenterology. 2011 Jul;141(1):269-78. doi: 10.1053/j.gastro.2011.03.052. Epub 2011 Apr 1. Gastroenterology. 2011. PMID: 21459094

10

Comparative proteomics of colon cancer stem cells and differentiated tumor cells identifies BIRC6 as a potential therapeutic target.

Van Houdt WJ, Emmink BL, Pham TV, Piersma SR, Verheem A, Vries RG, Fratantoni SA, Pronk A, Clevers H, Borel Rinkes IH, Jimenez CR, Kranenburg O. Van Houdt WJ, et al. Among authors: vries rg. Mol Cell Proteomics. 2011 Dec;10(12):M111.011353. doi: 10.1074/mcp.M111.011353. Epub 2011 Jul 25. Mol Cell Proteomics. 2011. PMID: 21788403 Free PMC article.

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