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Targeted Delivery of an Anti-inflammatory PDE4 Inhibitor to Immune Cells via an Antibody-drug Conjugate.
Yu S, Pearson AD, Lim RK, Rodgers DT, Li S, Parker HB, Weglarz M, Hampton EN, Bollong MJ, Shen J, Zambaldo C, Wang D, Woods AK, Wright TM, Schultz PG, Kazane SA, Young TS, Tremblay MS. Yu S, et al. Among authors: zambaldo c. Mol Ther. 2016 Dec;24(12):2078-2089. doi: 10.1038/mt.2016.175. Epub 2016 Oct 12. Mol Ther. 2016. PMID: 27731313 Free PMC article.
2-Sulfonylpyridines as Tunable, Cysteine-Reactive Electrophiles.
Zambaldo C, Vinogradova EV, Qi X, Iaconelli J, Suciu RM, Koh M, Senkane K, Chadwick SR, Sanchez BB, Chen JS, Chatterjee AK, Liu P, Schultz PG, Cravatt BF, Bollong MJ. Zambaldo C, et al. J Am Chem Soc. 2020 May 13;142(19):8972-8979. doi: 10.1021/jacs.0c02721. Epub 2020 Apr 29. J Am Chem Soc. 2020. PMID: 32302104 Free PMC article.
Recombinant thiopeptides containing noncanonical amino acids.
Luo X, Zambaldo C, Liu T, Zhang Y, Xuan W, Wang C, Reed SA, Yang PY, Wang RE, Javahishvili T, Schultz PG, Young TS. Luo X, et al. Among authors: zambaldo c. Proc Natl Acad Sci U S A. 2016 Mar 29;113(13):3615-20. doi: 10.1073/pnas.1602733113. Epub 2016 Mar 14. Proc Natl Acad Sci U S A. 2016. PMID: 26976568 Free PMC article.
YAP-dependent proliferation by a small molecule targeting annexin A2.
Shalhout SZ, Yang PY, Grzelak EM, Nutsch K, Shao S, Zambaldo C, Iaconelli J, Ibrahim L, Stanton C, Chadwick SR, Chen E, DeRan M, Li S, Hull M, Wu X, Chatterjee AK, Shen W, Camargo FD, Schultz PG, Bollong MJ. Shalhout SZ, et al. Among authors: zambaldo c. Nat Chem Biol. 2021 Jul;17(7):767-775. doi: 10.1038/s41589-021-00755-0. Epub 2021 Mar 15. Nat Chem Biol. 2021. PMID: 33723431
Genetically encoding phosphotyrosine and its nonhydrolyzable analog in bacteria.
Luo X, Fu G, Wang RE, Zhu X, Zambaldo C, Liu R, Liu T, Lyu X, Du J, Xuan W, Yao A, Reed SA, Kang M, Zhang Y, Guo H, Huang C, Yang PY, Wilson IA, Schultz PG, Wang F. Luo X, et al. Among authors: zambaldo c. Nat Chem Biol. 2017 Aug;13(8):845-849. doi: 10.1038/nchembio.2405. Epub 2017 Jun 12. Nat Chem Biol. 2017. PMID: 28604693 Free PMC article.
18 results