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Human CD40 ligand deficiency dysregulates the macrophage transcriptome causing functional defects that are improved by exogenous IFN-γ.
Cabral-Marques O, Ramos RN, Schimke LF, Khan TA, Amaral EP, Barbosa Bomfim CC, Junior OR, França TT, Arslanian C, Carola Correia Lima JD, Weber CW, Ferreira JF, Tavares FS, Sun J, D'Imperio Lima MR, Seelaender M, Garcia Calich VL, Marzagão Barbuto JA, Costa-Carvalho BT, Riemekasten G, Seminario G, Bezrodnik L, Notarangelo L, Torgerson TR, Ochs HD, Condino-Neto A. Cabral-Marques O, et al. J Allergy Clin Immunol. 2017 Mar;139(3):900-912.e7. doi: 10.1016/j.jaci.2016.07.018. Epub 2016 Aug 20. J Allergy Clin Immunol. 2017. PMID: 27554817
Cytosolic flagellin-induced lysosomal pathway regulates inflammasome-dependent and -independent macrophage responses.
Lage SL, Buzzo CL, Amaral EP, Matteucci KC, Massis LM, Icimoto MY, Carmona AK, D'Império Lima MR, Rodrigues MM, Ferreira LC, Amarante-Mendes GP, Bortoluci KR. Lage SL, et al. Proc Natl Acad Sci U S A. 2013 Aug 27;110(35):E3321-30. doi: 10.1073/pnas.1305316110. Epub 2013 Aug 13. Proc Natl Acad Sci U S A. 2013. PMID: 23942123 Free PMC article.
Pulmonary infection with hypervirulent Mycobacteria reveals a crucial role for the P2X7 receptor in aggressive forms of tuberculosis.
Amaral EP, Ribeiro SC, Lanes VR, Almeida FM, de Andrade MR, Bomfim CC, Salles EM, Bortoluci KR, Coutinho-Silva R, Hirata MH, Alvarez JM, Lasunskaia EB, D'Império-Lima MR. Amaral EP, et al. PLoS Pathog. 2014 Jul 3;10(7):e1004188. doi: 10.1371/journal.ppat.1004188. eCollection 2014 Jul. PLoS Pathog. 2014. PMID: 24991816 Free PMC article.
68 results