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A phase 1/2a, dose-escalation, safety, pharmacokinetic, and preliminary efficacy study of intraperitoneal administration of BC-819 (H19-DTA) in subjects with recurrent ovarian/peritoneal cancer.
Lavie O, Edelman D, Levy T, Fishman A, Hubert A, Segev Y, Raveh E, Gilon M, Hochberg A. Lavie O, et al. Among authors: hochberg a. Arch Gynecol Obstet. 2017 Mar;295(3):751-761. doi: 10.1007/s00404-017-4293-0. Epub 2017 Feb 3. Arch Gynecol Obstet. 2017. PMID: 28154921 Free PMC article. Clinical Trial.
Use of H19 Gene Regulatory Sequences in DNA-Based Therapy for Pancreatic Cancer.
Scaiewicz V, Sorin V, Fellig Y, Birman T, Mizrahi A, Galula J, Abu-Lail R, Shneider T, Ohana P, Buscail L, Hochberg A, Czerniak A. Scaiewicz V, et al. Among authors: hochberg a. J Oncol. 2010;2010:178174. doi: 10.1155/2010/178174. Epub 2010 Oct 28. J Oncol. 2010. PMID: 21052499 Free PMC article.
Characterization of human and mouse H19 regulatory sequences.
Banet G, Bibi O, Matouk I, Ayesh S, Laster M, Kimber KM, Tykocinski M, de Groot N, Hochberg A, Ohana P. Banet G, et al. Among authors: hochberg a. Mol Biol Rep. 2000 Sep;27(3):157-65. doi: 10.1023/a:1007139713781. Mol Biol Rep. 2000. PMID: 11254105
The product of the imprinted H19 gene is an oncofetal RNA.
Ariel I, Ayesh S, Perlman EJ, Pizov G, Tanos V, Schneider T, Erdmann VA, Podeh D, Komitowski D, Quasem AS, de Groot N, Hochberg A. Ariel I, et al. Among authors: hochberg a. Mol Pathol. 1997 Feb;50(1):34-44. doi: 10.1136/mp.50.1.34. Mol Pathol. 1997. PMID: 9208812 Free PMC article.
257 results