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Platelets induce apoptosis via membrane-bound FasL.
Schleicher RI, Reichenbach F, Kraft P, Kumar A, Lescan M, Todt F, Göbel K, Hilgendorf I, Geisler T, Bauer A, Olbrich M, Schaller M, Wesselborg S, O'Reilly L, Meuth SG, Schulze-Osthoff K, Gawaz M, Li X, Kleinschnitz C, Edlich F, Langer HF. Schleicher RI, et al. Blood. 2015 Sep 17;126(12):1483-93. doi: 10.1182/blood-2013-12-544445. Epub 2015 Jul 31. Blood. 2015. PMID: 26232171 Free PMC article.
Platelet derived FasL contributes to apoptosis in stroke.
Kraft P, Schleicher R, Olbrich M, Schuhmann MK, Blanz KD, Emschermann F, Ebenhoech S, Starz C, Hilgendorf I, Meuth SG, Edlich F, Kleinschnitz C, Langer HF. Kraft P, et al. Thromb Haemost. 2016 Oct 28;116(5):998-1000. doi: 10.1160/TH16-06-0447. Epub 2016 Aug 25. Thromb Haemost. 2016. PMID: 27608763 No abstract available.
Platelets contribute to the pathogenesis of experimental autoimmune encephalomyelitis.
Langer HF, Choi EY, Zhou H, Schleicher R, Chung KJ, Tang Z, Göbel K, Bdeir K, Chatzigeorgiou A, Wong C, Bhatia S, Kruhlak MJ, Rose JW, Burns JB, Hill KE, Qu H, Zhang Y, Lehrmann E, Becker KG, Wang Y, Simon DI, Nieswandt B, Lambris JD, Li X, Meuth SG, Kubes P, Chavakis T. Langer HF, et al. Circ Res. 2012 Apr 27;110(9):1202-10. doi: 10.1161/CIRCRESAHA.111.256370. Epub 2012 Mar 27. Circ Res. 2012. PMID: 22456181 Free PMC article.
Interruption of classic CD40L-CD40 signalling but not of the novel CD40L-Mac-1 interaction limits arterial neointima formation in mice.
Willecke F, Tiwari S, Rupprecht B, Wolf D, Hergeth S, Hoppe N, Dufner B, Schulte L, Anto Michel N, Bukosza N, Marchini T, Jäckel M, Stachon P, Hilgendorf I, Zeschky K, Schleicher R, Langer HF, von Zur Muhlen C, Bode C, Peter K, Zirlik A. Willecke F, et al. Thromb Haemost. 2014 Aug;112(2):379-89. doi: 10.1160/TH13-08-0653. Epub 2014 Mar 20. Thromb Haemost. 2014. PMID: 24652469